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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRS3
All Species:
37.27
Human Site:
S173
Identified Species:
74.55
UniProt:
O43559
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43559
NP_006644.1
492
54462
S173
T
S
S
L
R
H
P
S
L
G
E
E
S
T
H
Chimpanzee
Pan troglodytes
XP_001174236
492
54439
S173
T
S
S
L
R
H
P
S
L
G
E
E
S
T
H
Rhesus Macaque
Macaca mulatta
XP_001084538
492
54416
S173
T
S
S
L
R
H
P
S
L
G
E
E
S
T
H
Dog
Lupus familis
XP_538915
496
54822
S176
T
S
S
L
R
H
P
S
L
G
E
E
S
T
H
Cat
Felis silvestris
Mouse
Mus musculus
Q91WJ0
492
53957
S175
T
S
S
L
R
H
P
S
P
G
E
E
S
T
H
Rat
Rattus norvegicus
Q52RG8
492
54329
S175
T
S
S
L
R
H
P
S
P
G
E
E
S
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518131
552
59439
S206
A
G
S
L
R
H
S
S
L
G
E
E
S
T
H
Chicken
Gallus gallus
XP_418044
464
51898
S176
I
S
S
L
R
H
S
S
V
G
E
D
S
T
H
Frog
Xenopus laevis
NP_001085015
517
58232
S172
M
G
T
V
R
H
P
S
V
G
E
E
A
G
H
Zebra Danio
Brachydanio rerio
XP_001923962
485
53928
S169
V
G
S
T
R
L
P
S
V
G
E
E
S
T
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122793
483
53108
S184
S
Q
G
N
I
N
S
S
T
S
P
P
V
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781457
717
77816
E246
V
N
G
V
I
P
E
E
A
S
S
H
N
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
93.5
N.A.
86.1
88
N.A.
55.6
57.3
56.4
44.3
N.A.
N.A.
21.9
N.A.
24.1
Protein Similarity:
100
99.5
99.5
94.9
N.A.
89.6
90.8
N.A.
63.7
67.4
67.1
58.9
N.A.
N.A.
36.9
N.A.
37.9
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
80
73.3
53.3
66.6
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
80
86.6
80
73.3
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
9
9
0
0
84
75
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
25
17
0
0
0
0
0
0
84
0
0
0
9
0
% G
% His:
0
0
0
0
0
75
0
0
0
0
0
9
0
0
75
% H
% Ile:
9
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
67
0
9
0
0
42
0
0
0
0
9
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
9
0
9
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
9
67
0
17
0
9
9
0
0
9
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
84
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
59
75
0
0
0
25
92
0
17
9
0
75
0
9
% S
% Thr:
50
0
9
9
0
0
0
0
9
0
0
0
0
75
0
% T
% Val:
17
0
0
17
0
0
0
0
25
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _