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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRS3
All Species:
36.36
Human Site:
Y59
Identified Species:
72.73
UniProt:
O43559
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43559
NP_006644.1
492
54462
Y59
R
E
A
V
R
W
P
Y
L
C
L
R
R
Y
G
Chimpanzee
Pan troglodytes
XP_001174236
492
54439
Y59
R
E
A
V
R
W
P
Y
L
C
L
R
R
Y
G
Rhesus Macaque
Macaca mulatta
XP_001084538
492
54416
Y59
R
E
A
V
R
W
P
Y
L
C
L
R
R
Y
G
Dog
Lupus familis
XP_538915
496
54822
Y59
R
E
A
V
R
W
P
Y
L
C
L
R
R
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91WJ0
492
53957
Y59
R
E
A
V
R
W
P
Y
L
C
L
R
R
Y
G
Rat
Rattus norvegicus
Q52RG8
492
54329
Y59
Q
E
A
V
R
W
P
Y
L
C
L
R
R
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518131
552
59439
Y86
R
E
A
V
R
W
P
Y
L
C
L
R
R
Y
G
Chicken
Gallus gallus
XP_418044
464
51898
Y59
R
D
A
V
R
W
P
Y
L
C
L
R
R
Y
G
Frog
Xenopus laevis
NP_001085015
517
58232
C59
A
V
R
W
P
Y
L
C
L
R
R
Y
G
Y
D
Zebra Danio
Brachydanio rerio
XP_001923962
485
53928
Y59
R
D
A
V
K
W
P
Y
L
C
L
R
R
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122793
483
53108
F71
Y
D
A
E
I
F
S
F
E
S
G
R
R
C
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781457
717
77816
L61
A
E
T
V
K
W
P
L
R
C
L
R
R
Y
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
93.5
N.A.
86.1
88
N.A.
55.6
57.3
56.4
44.3
N.A.
N.A.
21.9
N.A.
24.1
Protein Similarity:
100
99.5
99.5
94.9
N.A.
89.6
90.8
N.A.
63.7
67.4
67.1
58.9
N.A.
N.A.
36.9
N.A.
37.9
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
100
93.3
13.3
86.6
N.A.
N.A.
20
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
20
100
N.A.
N.A.
40
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
84
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
84
0
0
0
9
0
% C
% Asp:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
67
0
9
0
0
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
84
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
9
9
84
0
84
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
84
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
67
0
9
0
67
0
0
0
9
9
9
92
92
0
0
% R
% Ser:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
9
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
9
0
84
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
9
0
84
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
9
0
75
0
0
0
9
0
92
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _