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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LAT All Species: 5.45
Human Site: T68 Identified Species: 20
UniProt: O43561 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43561 NP_001014987.1 262 27930 T68 P P A Y P P V T S Y P P L S Q
Chimpanzee Pan troglodytes XP_001147360 233 24969 S41 G S Y D S T S S D S L Y P R G
Rhesus Macaque Macaca mulatta XP_001102058 235 25115 S43 Y D S A S S D S L Y P R G I Q
Dog Lupus familis XP_849910 309 32869 P45 M E A V V L I P Y M L G L L L
Cat Felis silvestris
Mouse Mus musculus O54957 242 25996 S41 P V S Y D S T S T E S L Y P R
Rat Rattus norvegicus O70601 241 26174 S41 P A S Y D S A S T E S L Y P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_173435 193 20966
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.1 84.3 34.2 N.A. 61.8 59.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 88.5 87 42.3 N.A. 68.6 66.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 20 13.3 N.A. 13.3 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 33.3 20 N.A. 40 40 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 31.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 29 15 0 0 15 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 15 29 0 15 0 15 0 0 0 0 0 0 % D
% Glu: 0 15 0 0 0 0 0 0 0 29 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 0 0 0 0 0 0 0 0 0 0 15 15 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 15 0 0 0 0 0 0 15 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 15 0 0 15 0 29 29 29 15 15 % L
% Met: 15 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 43 15 0 0 15 15 0 15 0 0 29 15 15 29 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 29 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 15 0 15 29 % R
% Ser: 0 15 43 0 29 43 15 58 15 15 29 0 0 15 0 % S
% Thr: 0 0 0 0 0 15 15 15 29 0 0 0 0 0 0 % T
% Val: 0 15 0 15 15 0 15 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 15 0 15 43 0 0 0 0 15 29 0 15 29 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _