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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS14
All Species:
25.45
Human Site:
S288
Identified Species:
70
UniProt:
O43566
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43566
NP_006471.2
566
61447
S288
K
S
E
S
H
R
K
S
L
G
S
T
E
G
E
Chimpanzee
Pan troglodytes
XP_001142206
567
61518
S288
K
S
E
S
H
R
K
S
L
G
S
T
E
G
E
Rhesus Macaque
Macaca mulatta
XP_001089197
566
61537
S287
K
S
E
S
H
R
K
S
L
G
S
T
E
G
E
Dog
Lupus familis
XP_546208
565
61124
S286
K
S
E
S
H
R
K
S
L
G
S
T
E
G
E
Cat
Felis silvestris
Mouse
Mus musculus
P97492
547
59815
S289
K
S
E
S
H
R
K
S
L
G
S
G
E
S
E
Rat
Rattus norvegicus
O08773
544
59473
S286
K
S
E
S
H
R
K
S
L
G
S
G
E
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520051
772
84545
E274
A
A
S
L
E
L
S
E
T
Y
R
L
S
V
S
Chicken
Gallus gallus
XP_420820
1393
153801
S943
S
L
D
L
S
E
A
S
R
L
P
A
F
V
P
Frog
Xenopus laevis
NP_001085707
661
73004
S291
K
S
E
N
E
G
G
S
T
G
S
T
D
P
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98
88.3
N.A.
85.1
83.7
N.A.
29.6
20.1
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
98.9
91.3
N.A.
88.1
87.2
N.A.
44.5
29
59.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
0
6.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
6.6
13.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
0
0
0
12
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
0
0
0
0
0
0
12
0
0
% D
% Glu:
0
0
78
0
23
12
0
12
0
0
0
0
67
0
78
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
0
0
0
0
12
12
0
0
78
0
23
0
56
0
% G
% His:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
78
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
0
23
0
12
0
0
67
12
0
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
12
0
0
12
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
67
0
0
12
0
12
0
0
0
0
% R
% Ser:
12
78
12
67
12
0
12
89
0
0
78
0
12
12
12
% S
% Thr:
0
0
0
0
0
0
0
0
23
0
0
56
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _