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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CA12
All Species:
1.52
Human Site:
S331
Identified Species:
3.7
UniProt:
O43570
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.44
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43570
NP_001209.1
354
39451
S331
I
W
L
F
R
R
K
S
I
K
K
G
D
N
K
Chimpanzee
Pan troglodytes
Q7M317
261
28893
A239
S
N
V
E
G
D
N
A
V
P
M
Q
H
N
N
Rhesus Macaque
Macaca mulatta
P00916
261
28918
P239
S
N
V
E
G
S
N
P
V
P
I
Q
R
N
N
Dog
Lupus familis
XP_535507
381
42561
K358
I
W
L
F
R
R
K
K
S
K
K
G
D
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI85
354
39677
K331
I
W
L
F
K
R
K
K
S
K
K
G
D
N
K
Rat
Rattus norvegicus
B0BNN3
261
28281
A239
S
S
A
E
G
E
P
A
V
P
V
L
S
N
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520237
436
47773
K414
F
R
R
R
K
T
K
K
G
E
D
N
K
G
V
Chicken
Gallus gallus
XP_413756
342
39061
T319
L
C
R
R
K
S
C
T
K
E
E
N
R
E
V
Frog
Xenopus laevis
NP_001091227
337
37600
K315
R
T
K
R
S
S
R
K
P
S
D
N
R
N
V
Zebra Danio
Brachydanio rerio
Q92051
260
28659
C238
S
S
E
G
E
T
P
C
C
M
V
D
N
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.8
25.7
73.4
N.A.
81.9
30.2
N.A.
43.1
56.5
48.3
27.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
42.9
42
81
N.A.
87.2
45.7
N.A.
54.8
72.3
64.6
42.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
86.6
N.A.
80
6.6
N.A.
6.6
0
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
20
86.6
N.A.
86.6
20
N.A.
20
33.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
20
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
10
10
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
20
10
30
0
0
% D
% Glu:
0
0
10
30
10
10
0
0
0
20
10
0
0
10
0
% E
% Phe:
10
0
0
30
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
30
0
0
0
10
0
0
30
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% H
% Ile:
30
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% I
% Lys:
0
0
10
0
30
0
40
40
10
30
30
0
10
0
30
% K
% Leu:
10
0
30
0
0
0
0
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% M
% Asn:
0
20
0
0
0
0
20
0
0
0
0
30
10
70
20
% N
% Pro:
0
0
0
0
0
0
20
10
10
30
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% Q
% Arg:
10
10
20
30
20
30
10
0
0
0
0
0
30
0
10
% R
% Ser:
40
20
0
0
10
30
0
10
20
10
0
0
10
0
0
% S
% Thr:
0
10
0
0
0
20
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
20
0
0
0
0
0
30
0
20
0
0
0
30
% V
% Trp:
0
30
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _