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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKAP10
All Species:
12.73
Human Site:
S212
Identified Species:
23.33
UniProt:
O43572
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43572
NP_009133.2
662
73818
S212
K
R
L
E
D
S
G
S
A
Q
L
F
M
T
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099682
643
71871
E205
M
T
H
S
E
G
I
E
L
N
N
R
T
N
S
Dog
Lupus familis
XP_851367
662
73924
S212
K
R
L
E
D
S
S
S
A
Q
L
L
M
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
O88845
662
73613
S212
R
R
L
G
D
S
S
S
A
P
L
L
V
T
Q
Rat
Rattus norvegicus
NP_001108078
662
73756
S212
R
R
L
G
D
S
S
S
A
P
L
L
L
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508501
708
79092
S216
D
K
R
L
E
D
S
S
T
V
Q
L
L
V
T
Chicken
Gallus gallus
XP_415856
639
71234
R206
V
T
P
D
K
S
D
R
T
H
N
S
R
N
H
Frog
Xenopus laevis
NP_001084758
636
71076
Q205
G
L
D
T
G
A
K
Q
T
S
A
S
N
H
L
Zebra Danio
Brachydanio rerio
XP_695298
653
72913
P206
T
S
S
R
P
H
T
P
S
P
Q
D
T
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609783
622
69650
T196
L
S
M
R
K
P
L
T
D
D
E
K
S
R
I
Honey Bee
Apis mellifera
XP_001122405
513
59382
Q87
Q
L
S
K
T
L
P
Q
I
L
A
D
K
G
A
Nematode Worm
Caenorhab. elegans
Q10955
492
55905
S65
S
A
D
I
G
S
G
S
D
H
E
G
I
I
V
Sea Urchin
Strong. purpuratus
XP_001203361
588
65696
E161
V
S
V
H
K
E
S
E
S
P
S
R
S
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.4
94.7
N.A.
89.7
90.9
N.A.
78.2
80
70.6
66
N.A.
26.2
30.2
21.7
34.5
Protein Similarity:
100
N.A.
96
96.8
N.A.
94.2
95
N.A.
84
86.8
79.4
77.7
N.A.
44.5
48.3
37.9
54
P-Site Identity:
100
N.A.
0
80
N.A.
53.3
53.3
N.A.
6.6
13.3
0
0
N.A.
0
0
20
0
P-Site Similarity:
100
N.A.
6.6
80
N.A.
66.6
66.6
N.A.
26.6
20
6.6
6.6
N.A.
13.3
13.3
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
0
31
0
16
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
16
8
31
8
8
0
16
8
0
16
0
0
0
% D
% Glu:
0
0
0
16
16
8
0
16
0
0
16
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
0
16
16
8
16
0
0
0
0
8
0
8
0
% G
% His:
0
0
8
8
0
8
0
0
0
16
0
0
0
8
16
% H
% Ile:
0
0
0
8
0
0
8
0
8
0
0
0
8
8
8
% I
% Lys:
16
8
0
8
24
0
8
0
0
0
0
8
8
0
0
% K
% Leu:
8
16
31
8
0
8
8
0
8
8
31
31
16
0
8
% L
% Met:
8
0
8
0
0
0
0
0
0
0
0
0
16
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
16
0
8
24
0
% N
% Pro:
0
0
8
0
8
8
8
8
0
31
0
0
0
8
0
% P
% Gln:
8
0
0
0
0
0
0
16
0
16
16
0
0
0
31
% Q
% Arg:
16
31
8
16
0
0
0
8
0
0
0
16
8
8
0
% R
% Ser:
8
24
16
8
0
47
39
47
16
8
8
16
16
0
16
% S
% Thr:
8
16
0
8
8
0
8
8
24
0
0
0
16
31
8
% T
% Val:
16
0
8
0
0
0
0
0
0
8
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _