KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYT7
All Species:
20.3
Human Site:
T252
Identified Species:
40.61
UniProt:
O43581
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43581
NP_004191.2
403
45501
T252
V
D
L
T
Q
M
Q
T
F
W
K
D
L
K
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118525
997
107105
T846
V
D
L
T
Q
M
Q
T
F
W
K
D
L
K
P
Dog
Lupus familis
XP_540917
681
75040
T530
V
D
L
T
Q
M
Q
T
F
W
K
D
L
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0N7
403
45454
T252
V
D
L
T
Q
M
Q
T
F
W
K
D
L
K
P
Rat
Rattus norvegicus
P29101
422
47191
E259
D
L
G
Q
P
I
E
E
W
R
D
L
Q
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519609
246
27030
V119
S
G
T
S
D
P
F
V
K
I
Y
L
L
P
D
Chicken
Gallus gallus
P47191
424
47487
E261
D
F
G
H
V
T
E
E
W
R
D
L
Q
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662797
544
60383
T393
V
E
L
V
P
M
Q
T
L
W
K
E
L
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21521
474
53246
E309
I
D
L
A
Q
T
I
E
E
W
R
D
L
V
S
Honey Bee
Apis mellifera
XP_392664
416
45935
S264
V
D
F
S
D
K
P
S
F
W
K
A
L
K
P
Nematode Worm
Caenorhab. elegans
P34693
441
49885
E276
D
L
G
A
V
I
E
E
W
K
D
I
A
P
P
Sea Urchin
Strong. purpuratus
XP_001191249
404
45603
L251
I
D
L
T
H
E
K
L
Y
W
R
S
L
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
39.6
53.8
N.A.
98.2
36.4
N.A.
49.6
35.8
N.A.
55.1
N.A.
35
41.3
35.5
43.3
Protein Similarity:
100
N.A.
40.3
56.3
N.A.
99.2
55.2
N.A.
52.8
54.2
N.A.
62.3
N.A.
52.7
58.8
54.8
62.3
P-Site Identity:
100
N.A.
100
100
N.A.
100
0
N.A.
6.6
0
N.A.
66.6
N.A.
40
53.3
6.6
40
P-Site Similarity:
100
N.A.
100
100
N.A.
100
20
N.A.
13.3
13.3
N.A.
80
N.A.
53.3
66.6
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
0
0
0
0
0
0
9
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
59
0
0
17
0
0
0
0
0
25
42
0
0
9
% D
% Glu:
0
9
0
0
0
9
25
34
9
0
0
9
0
0
0
% E
% Phe:
0
9
9
0
0
0
9
0
42
0
0
0
0
0
0
% F
% Gly:
0
9
25
0
0
0
0
0
0
0
0
0
0
9
9
% G
% His:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
17
9
0
0
9
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
9
9
0
9
9
50
0
0
50
0
% K
% Leu:
0
17
59
0
0
0
0
9
9
0
0
25
75
0
0
% L
% Met:
0
0
0
0
0
42
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
17
9
9
0
0
0
0
0
0
17
67
% P
% Gln:
0
0
0
9
42
0
42
0
0
0
0
0
17
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
17
17
0
0
0
0
% R
% Ser:
9
0
0
17
0
0
0
9
0
0
0
9
0
9
9
% S
% Thr:
0
0
9
42
0
17
0
42
0
0
0
0
0
9
0
% T
% Val:
50
0
0
9
17
0
0
9
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
25
67
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _