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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYT7
All Species:
26.67
Human Site:
Y226
Identified Species:
53.33
UniProt:
O43581
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43581
NP_004191.2
403
45501
Y226
L
Y
L
Q
V
L
D
Y
D
R
F
S
R
N
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118525
997
107105
Y820
L
Y
L
Q
V
L
D
Y
D
R
F
S
R
N
D
Dog
Lupus familis
XP_540917
681
75040
Y504
L
Y
L
Q
V
L
D
Y
D
R
F
S
R
N
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0N7
403
45454
Y226
L
Y
L
Q
V
L
D
Y
D
R
F
S
R
N
D
Rat
Rattus norvegicus
P29101
422
47191
D233
V
M
A
I
Y
D
F
D
R
F
S
K
H
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519609
246
27030
E93
S
V
G
Y
N
F
Q
E
S
T
L
T
V
K
I
Chicken
Gallus gallus
P47191
424
47487
D235
V
M
A
V
Y
D
F
D
R
F
S
K
H
D
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662797
544
60383
Y367
L
Y
L
Q
V
L
D
Y
D
R
F
S
R
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21521
474
53246
F283
L
V
F
A
I
F
D
F
D
R
F
S
K
H
D
Honey Bee
Apis mellifera
XP_392664
416
45935
Y238
L
H
L
H
V
F
D
Y
D
R
F
S
R
D
D
Nematode Worm
Caenorhab. elegans
P34693
441
49885
D250
V
F
A
I
Y
D
F
D
R
F
S
K
H
D
Q
Sea Urchin
Strong. purpuratus
XP_001191249
404
45603
Y225
L
H
L
Q
V
L
D
Y
D
R
F
S
R
N
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
39.6
53.8
N.A.
98.2
36.4
N.A.
49.6
35.8
N.A.
55.1
N.A.
35
41.3
35.5
43.3
Protein Similarity:
100
N.A.
40.3
56.3
N.A.
99.2
55.2
N.A.
52.8
54.2
N.A.
62.3
N.A.
52.7
58.8
54.8
62.3
P-Site Identity:
100
N.A.
100
100
N.A.
100
0
N.A.
0
0
N.A.
100
N.A.
46.6
73.3
0
93.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
6.6
13.3
N.A.
100
N.A.
73.3
86.6
20
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
9
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
25
67
25
67
0
0
0
0
34
67
% D
% Glu:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
9
9
0
0
25
25
9
0
25
67
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
17
0
9
0
0
0
0
0
0
0
0
25
9
0
% H
% Ile:
0
0
0
17
9
0
0
0
0
0
0
0
0
0
25
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
25
9
9
0
% K
% Leu:
67
0
59
0
0
50
0
0
0
0
9
0
0
0
0
% L
% Met:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
0
50
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
50
0
0
9
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
25
67
0
0
59
0
0
% R
% Ser:
9
0
0
0
0
0
0
0
9
0
25
67
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% T
% Val:
25
17
0
9
59
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
42
0
9
25
0
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _