KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DENR
All Species:
11.82
Human Site:
S81
Identified Species:
20
UniProt:
O43583
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43583
NP_003668.2
198
22092
S81
P
K
Q
E
A
G
I
S
E
G
Q
G
T
A
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095611
732
83804
R81
N
K
K
L
E
L
V
R
V
K
E
Q
Q
G
K
Dog
Lupus familis
XP_853345
423
44845
S306
P
K
Q
E
A
G
I
S
E
G
Q
G
T
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQJ6
198
22148
T81
P
K
Q
E
T
G
I
T
E
G
Q
G
P
V
G
Rat
Rattus norvegicus
NP_001108518
194
21730
S77
P
K
Q
E
T
G
I
S
E
G
Q
G
P
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506956
172
19464
K71
E
E
E
K
K
K
Q
K
R
G
G
R
G
Q
I
Chicken
Gallus gallus
Q5ZJ39
198
22140
G81
P
K
Q
E
A
G
V
G
E
G
Q
G
T
A
G
Frog
Xenopus laevis
Q6GLZ1
198
22202
V81
P
K
Q
E
T
G
T
V
E
G
Q
A
T
S
G
Zebra Danio
Brachydanio rerio
Q6DH65
208
22785
G79
P
K
Q
E
S
K
G
G
G
G
G
E
D
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573176
189
21331
D79
A
A
A
A
D
G
T
D
D
D
K
K
R
Q
K
Honey Bee
Apis mellifera
XP_624918
182
20586
E73
N
T
E
V
G
G
G
E
D
E
K
K
R
Q
K
Nematode Worm
Caenorhab. elegans
Q9NAH4
192
20331
K78
A
D
G
D
E
K
K
K
Q
K
R
G
G
K
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47089
198
22476
K74
A
R
E
E
K
L
E
K
D
L
L
K
I
Q
K
Red Bread Mold
Neurospora crassa
Q9P3T4
187
20737
K74
A
M
K
D
A
K
K
K
A
A
K
A
E
A
A
Conservation
Percent
Protein Identity:
100
N.A.
20.3
46
N.A.
96.4
94.9
N.A.
84.3
91.4
83.3
77.4
N.A.
47.4
53.5
40.9
N.A.
Protein Similarity:
100
N.A.
24.4
46.5
N.A.
97.4
95.4
N.A.
85.3
94.9
90.4
83.6
N.A.
70.1
72.2
57
N.A.
P-Site Identity:
100
N.A.
6.6
100
N.A.
73.3
80
N.A.
6.6
86.6
66.6
40
N.A.
6.6
6.6
13.3
N.A.
P-Site Similarity:
100
N.A.
26.6
100
N.A.
80
80
N.A.
26.6
93.3
73.3
46.6
N.A.
20
26.6
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.7
39.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.4
56.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
8
8
8
29
0
0
0
8
8
0
15
0
29
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
15
8
0
0
8
22
8
0
0
8
0
0
% D
% Glu:
8
8
22
58
15
0
8
8
43
8
8
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
8
58
15
15
8
58
15
43
15
15
58
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
29
0
0
0
0
0
8
0
8
% I
% Lys:
0
58
15
8
15
29
15
29
0
15
22
22
0
8
29
% K
% Leu:
0
0
0
8
0
15
0
0
0
8
8
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
50
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% P
% Gln:
0
0
50
0
0
0
8
0
8
0
43
8
8
29
0
% Q
% Arg:
0
8
0
0
0
0
0
8
8
0
8
8
15
0
0
% R
% Ser:
0
0
0
0
8
0
0
22
0
0
0
0
0
8
0
% S
% Thr:
0
8
0
0
22
0
15
8
0
0
0
0
29
0
0
% T
% Val:
0
0
0
8
0
0
15
8
8
0
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _