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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DENR
All Species:
35.76
Human Site:
Y127
Identified Species:
60.51
UniProt:
O43583
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43583
NP_003668.2
198
22092
Y127
I
P
R
A
K
K
K
Y
V
T
R
V
C
G
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095611
732
83804
L126
I
E
K
Q
R
K
E
L
Q
L
L
I
G
E
L
Dog
Lupus familis
XP_853345
423
44845
Y352
I
P
R
A
K
K
K
Y
V
T
R
V
C
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQJ6
198
22148
Y127
I
P
R
A
K
K
K
Y
V
T
R
V
C
G
L
Rat
Rattus norvegicus
NP_001108518
194
21730
Y123
I
P
R
A
K
K
K
Y
V
T
R
V
C
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506956
172
19464
L108
Y
V
T
R
V
C
G
L
A
T
F
E
I
D
L
Chicken
Gallus gallus
Q5ZJ39
198
22140
Y127
I
P
R
A
K
K
K
Y
V
T
R
V
C
G
L
Frog
Xenopus laevis
Q6GLZ1
198
22202
Y127
I
P
R
A
K
K
K
Y
V
T
R
V
C
G
L
Zebra Danio
Brachydanio rerio
Q6DH65
208
22785
Y137
I
P
R
A
K
K
K
Y
V
T
R
V
C
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573176
189
21331
S117
A
A
R
G
K
K
K
S
V
T
V
V
T
G
L
Honey Bee
Apis mellifera
XP_624918
182
20586
S111
A
P
R
G
K
K
K
S
V
T
V
V
T
G
L
Nematode Worm
Caenorhab. elegans
Q9NAH4
192
20331
S121
R
E
P
R
G
K
K
S
V
T
V
I
K
G
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47089
198
22476
F111
E
A
R
T
K
R
K
F
I
V
A
I
S
G
L
Red Bread Mold
Neurospora crassa
Q9P3T4
187
20737
S111
R
K
Y
V
T
S
V
S
G
L
E
A
F
G
L
Conservation
Percent
Protein Identity:
100
N.A.
20.3
46
N.A.
96.4
94.9
N.A.
84.3
91.4
83.3
77.4
N.A.
47.4
53.5
40.9
N.A.
Protein Similarity:
100
N.A.
24.4
46.5
N.A.
97.4
95.4
N.A.
85.3
94.9
90.4
83.6
N.A.
70.1
72.2
57
N.A.
P-Site Identity:
100
N.A.
20
100
N.A.
100
100
N.A.
13.3
100
100
100
N.A.
60
66.6
40
N.A.
P-Site Similarity:
100
N.A.
46.6
100
N.A.
100
100
N.A.
13.3
100
100
100
N.A.
60
66.6
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.7
39.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.4
56.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
0
50
0
0
0
0
8
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
50
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
8
15
0
0
0
0
8
0
0
0
8
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
0
8
0
0
% F
% Gly:
0
0
0
15
8
0
8
0
8
0
0
0
8
86
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
58
0
0
0
0
0
0
0
8
0
0
22
8
0
0
% I
% Lys:
0
8
8
0
72
79
79
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
15
0
15
8
0
0
0
100
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
58
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
15
0
72
15
8
8
0
0
0
0
50
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
29
0
0
0
0
8
0
0
% S
% Thr:
0
0
8
8
8
0
0
0
0
79
0
0
15
0
0
% T
% Val:
0
8
0
8
8
0
8
0
72
8
22
65
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _