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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPOT
All Species:
19.39
Human Site:
S433
Identified Species:
32.82
UniProt:
O43592
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43592
NP_009166.2
962
109964
S433
S
V
R
R
V
F
S
S
T
L
Q
N
W
Q
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116910
962
109962
S433
S
V
R
R
V
F
S
S
T
L
Q
N
W
Q
T
Dog
Lupus familis
XP_531658
962
110054
S433
S
V
R
R
V
F
S
S
T
L
Q
N
W
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CRT8
963
109715
A434
S
V
R
R
V
F
S
A
T
L
Q
N
W
Q
T
Rat
Rattus norvegicus
NP_001101572
728
83466
K269
K
G
M
D
P
V
D
K
M
K
L
V
E
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508666
962
109919
T433
S
V
R
R
V
F
S
T
T
L
Q
N
W
Q
A
Chicken
Gallus gallus
XP_416065
962
109808
T433
S
V
R
R
V
F
N
T
T
L
Q
N
W
Q
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5SPJ8
961
109329
A433
A
V
H
R
V
F
N
A
T
M
Q
S
W
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_501320
950
105658
E431
A
V
E
P
W
T
A
E
V
T
S
G
G
S
S
Sea Urchin
Strong. purpuratus
XP_786292
944
107893
E433
S
V
H
S
V
V
M
E
T
L
G
H
W
R
S
Poplar Tree
Populus trichocarpa
XP_002304132
994
112620
S449
F
I
R
N
S
L
V
S
C
I
S
S
V
S
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177400
988
111444
N445
F
I
R
N
S
L
A
N
A
V
E
S
S
S
E
Baker's Yeast
Sacchar. cerevisiae
P33418
1100
126801
A476
N
I
S
Q
E
I
S
A
N
L
M
N
C
K
N
Red Bread Mold
Neurospora crassa
Q7RWV9
1026
114793
E467
G
N
M
F
A
T
L
E
Q
Q
G
P
Q
M
D
Conservation
Percent
Protein Identity:
100
N.A.
99.9
99.2
N.A.
95
68.6
N.A.
94.9
93.8
N.A.
78.4
N.A.
N.A.
N.A.
25.5
50.8
Protein Similarity:
100
N.A.
100
99.9
N.A.
98.2
72.2
N.A.
98.2
98.1
N.A.
89.9
N.A.
N.A.
N.A.
47.1
70.2
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
0
N.A.
86.6
86.6
N.A.
60
N.A.
N.A.
N.A.
6.6
40
P-Site Similarity:
100
N.A.
100
100
N.A.
100
0
N.A.
93.3
100
N.A.
93.3
N.A.
N.A.
N.A.
26.6
60
Percent
Protein Identity:
28.1
N.A.
N.A.
28.5
20.2
25.8
Protein Similarity:
50.4
N.A.
N.A.
50.7
42.3
45.4
P-Site Identity:
13.3
N.A.
N.A.
6.6
20
0
P-Site Similarity:
33.3
N.A.
N.A.
46.6
53.3
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
8
0
15
22
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
8
0
8
0
0
22
0
0
8
0
8
0
15
% E
% Phe:
15
0
0
8
0
50
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
0
0
0
0
0
0
0
15
8
8
0
0
% G
% His:
0
0
15
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
22
0
0
0
8
0
0
0
8
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
8
0
8
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
15
8
0
0
58
8
0
0
0
8
% L
% Met:
0
0
15
0
0
0
8
0
8
8
8
0
0
8
0
% M
% Asn:
8
8
0
15
0
0
15
8
8
0
0
50
0
0
8
% N
% Pro:
0
0
0
8
8
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
8
8
50
0
8
50
0
% Q
% Arg:
0
0
58
50
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
50
0
8
8
15
0
43
29
0
0
15
22
8
29
15
% S
% Thr:
0
0
0
0
0
15
0
15
58
8
0
0
0
0
43
% T
% Val:
0
65
0
0
58
15
8
0
8
8
0
8
8
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
58
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _