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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPOT
All Species:
29.39
Human Site:
S536
Identified Species:
49.74
UniProt:
O43592
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43592
NP_009166.2
962
109964
S536
D
H
R
G
L
R
H
S
S
A
K
V
R
S
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116910
962
109962
S536
D
H
R
G
L
R
H
S
S
A
K
V
R
S
R
Dog
Lupus familis
XP_531658
962
110054
S536
D
H
R
G
L
R
H
S
S
A
K
V
R
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CRT8
963
109715
S537
D
H
R
G
L
W
H
S
S
A
K
V
R
S
R
Rat
Rattus norvegicus
NP_001101572
728
83466
H365
G
F
C
Y
D
Y
L
H
I
L
K
Q
L
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508666
962
109919
S536
D
H
R
G
L
R
H
S
S
P
K
V
R
S
R
Chicken
Gallus gallus
XP_416065
962
109808
S536
D
H
R
G
L
R
H
S
S
P
K
V
R
S
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5SPJ8
961
109329
S536
D
H
R
G
L
R
H
S
S
P
K
V
R
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_501320
950
105658
S534
D
Q
R
G
I
S
I
S
S
A
N
V
R
T
R
Sea Urchin
Strong. purpuratus
XP_786292
944
107893
R536
D
D
R
G
L
R
H
R
H
P
T
V
R
S
R
Poplar Tree
Populus trichocarpa
XP_002304132
994
112620
P546
D
E
R
G
I
H
H
P
N
F
H
V
R
R
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177400
988
111444
Q542
D
D
R
G
L
H
H
Q
N
F
Y
V
S
R
R
Baker's Yeast
Sacchar. cerevisiae
P33418
1100
126801
K594
S
S
F
A
M
F
N
K
R
E
N
V
R
L
R
Red Bread Mold
Neurospora crassa
Q7RWV9
1026
114793
E568
F
V
H
L
I
H
H
E
H
P
R
V
R
T
R
Conservation
Percent
Protein Identity:
100
N.A.
99.9
99.2
N.A.
95
68.6
N.A.
94.9
93.8
N.A.
78.4
N.A.
N.A.
N.A.
25.5
50.8
Protein Similarity:
100
N.A.
100
99.9
N.A.
98.2
72.2
N.A.
98.2
98.1
N.A.
89.9
N.A.
N.A.
N.A.
47.1
70.2
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
13.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
N.A.
N.A.
60
66.6
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
13.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
N.A.
N.A.
73.3
66.6
Percent
Protein Identity:
28.1
N.A.
N.A.
28.5
20.2
25.8
Protein Similarity:
50.4
N.A.
N.A.
50.7
42.3
45.4
P-Site Identity:
46.6
N.A.
N.A.
46.6
20
26.6
P-Site Similarity:
60
N.A.
N.A.
53.3
33.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
36
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
79
15
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
8
0
8
0
0
0
0
0
% E
% Phe:
8
8
8
0
0
8
0
0
0
15
0
0
0
0
0
% F
% Gly:
8
0
0
79
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
50
8
0
0
22
79
8
15
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
22
0
8
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
58
0
0
0
0
% K
% Leu:
0
0
0
8
65
0
8
0
0
8
0
0
8
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
15
0
15
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
36
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
8
0
0
0
8
0
0
0
% Q
% Arg:
0
0
79
0
0
50
0
8
8
0
8
0
86
15
93
% R
% Ser:
8
8
0
0
0
8
0
58
58
0
0
0
8
65
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
0
15
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
93
0
0
8
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _