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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XPOT All Species: 11.52
Human Site: T362 Identified Species: 19.49
UniProt: O43592 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43592 NP_009166.2 962 109964 T362 L H I L K Q L T V L S D Q Q K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001116910 962 109962 T362 L H I L K Q L T V L S D Q Q K
Dog Lupus familis XP_531658 962 110054 P362 L H I L K Q L P V L S D Q Q K
Cat Felis silvestris
Mouse Mus musculus Q9CRT8 963 109715 P363 L H I L K Q L P V L S D Q Q K
Rat Rattus norvegicus NP_001101572 728 83466 N202 S W Y Q I L H N Y Q Y T N S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508666 962 109919 A362 L H I L K Q L A V L S D Q Q K
Chicken Gallus gallus XP_416065 962 109808 S362 L H I L K Q L S A L S D Q Q K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5SPJ8 961 109329 P362 L H V L K Q L P A L N E Q Q K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_501320 950 105658 L359 I R A Y C S F L L K F H P N E
Sea Urchin Strong. purpuratus XP_786292 944 107893 G362 I G I L K Q I G T L N E S Q I
Poplar Tree Populus trichocarpa XP_002304132 994 112620 S372 V T T M K S L S P L R E K Q L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_177400 988 111444 P368 V S T L K G L P A L K E K Q L
Baker's Yeast Sacchar. cerevisiae P33418 1100 126801 K403 L A F L K K Y K A S S P N F V
Red Bread Mold Neurospora crassa Q7RWV9 1026 114793 G388 L T F L R R V G T L P D S Y S
Conservation
Percent
Protein Identity: 100 N.A. 99.9 99.2 N.A. 95 68.6 N.A. 94.9 93.8 N.A. 78.4 N.A. N.A. N.A. 25.5 50.8
Protein Similarity: 100 N.A. 100 99.9 N.A. 98.2 72.2 N.A. 98.2 98.1 N.A. 89.9 N.A. N.A. N.A. 47.1 70.2
P-Site Identity: 100 N.A. 100 93.3 N.A. 93.3 0 N.A. 93.3 86.6 N.A. 66.6 N.A. N.A. N.A. 0 40
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 6.6 N.A. 93.3 93.3 N.A. 86.6 N.A. N.A. N.A. 20 66.6
Percent
Protein Identity: 28.1 N.A. N.A. 28.5 20.2 25.8
Protein Similarity: 50.4 N.A. N.A. 50.7 42.3 45.4
P-Site Identity: 26.6 N.A. N.A. 33.3 26.6 26.6
P-Site Similarity: 60 N.A. N.A. 53.3 33.3 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 0 8 29 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 29 0 0 15 % E
% Phe: 0 0 15 0 0 0 8 0 0 0 8 0 0 8 0 % F
% Gly: 0 8 0 0 0 8 0 15 0 0 0 0 0 0 0 % G
% His: 0 50 0 0 0 0 8 0 0 0 0 8 0 0 0 % H
% Ile: 15 0 50 0 8 0 8 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 79 8 0 8 0 8 8 0 15 0 50 % K
% Leu: 65 0 0 79 0 8 65 8 8 79 0 0 0 0 15 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 15 0 15 8 0 % N
% Pro: 0 0 0 0 0 0 0 29 8 0 8 8 8 0 0 % P
% Gln: 0 0 0 8 0 58 0 0 0 8 0 0 50 72 0 % Q
% Arg: 0 8 0 0 8 8 0 0 0 0 8 0 0 0 0 % R
% Ser: 8 8 0 0 0 15 0 15 0 8 50 0 15 8 8 % S
% Thr: 0 15 15 0 0 0 0 15 15 0 0 8 0 0 0 % T
% Val: 15 0 8 0 0 0 8 0 36 0 0 0 0 0 8 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 8 0 0 8 0 8 0 8 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _