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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XPOT All Species: 32.12
Human Site: T544 Identified Species: 54.36
UniProt: O43592 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43592 NP_009166.2 962 109964 T544 S A K V R S R T A Y L F S R F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001116910 962 109962 T544 S A K V R S R T A Y L F S R F
Dog Lupus familis XP_531658 962 110054 T544 S A K V R S R T A Y L F S R F
Cat Felis silvestris
Mouse Mus musculus Q9CRT8 963 109715 T545 S A K V R S R T A Y L F S R F
Rat Rattus norvegicus NP_001101572 728 83466 L373 I L K Q L S V L S D Q Q K A N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508666 962 109919 T544 S P K V R S R T A Y L F S R F
Chicken Gallus gallus XP_416065 962 109808 T544 S P K V R S R T A Y L F S R F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5SPJ8 961 109329 V544 S P K V R S R V A Y L F S R F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_501320 950 105658 I542 S A N V R T R I V Y L F C R F
Sea Urchin Strong. purpuratus XP_786292 944 107893 S544 H P T V R S R S A Y L F T R F
Poplar Tree Populus trichocarpa XP_002304132 994 112620 A554 N F H V R R R A S Y L F M R V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_177400 988 111444 A550 N F Y V S R R A G Y L F M R V
Baker's Yeast Sacchar. cerevisiae P33418 1100 126801 S602 R E N V R L R S W Y L F T R F
Red Bread Mold Neurospora crassa Q7RWV9 1026 114793 S576 H P R V R T R S W Y L F L R F
Conservation
Percent
Protein Identity: 100 N.A. 99.9 99.2 N.A. 95 68.6 N.A. 94.9 93.8 N.A. 78.4 N.A. N.A. N.A. 25.5 50.8
Protein Similarity: 100 N.A. 100 99.9 N.A. 98.2 72.2 N.A. 98.2 98.1 N.A. 89.9 N.A. N.A. N.A. 47.1 70.2
P-Site Identity: 100 N.A. 100 100 N.A. 100 13.3 N.A. 93.3 93.3 N.A. 86.6 N.A. N.A. N.A. 66.6 66.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 20 N.A. 93.3 93.3 N.A. 86.6 N.A. N.A. N.A. 73.3 80
Percent
Protein Identity: 28.1 N.A. N.A. 28.5 20.2 25.8
Protein Similarity: 50.4 N.A. N.A. 50.7 42.3 45.4
P-Site Identity: 46.6 N.A. N.A. 40 53.3 53.3
P-Site Similarity: 60 N.A. N.A. 46.6 66.6 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 36 0 0 0 0 0 15 58 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 15 0 0 0 0 0 0 0 0 0 93 0 0 79 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % G
% His: 15 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 58 0 0 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 8 0 0 8 8 0 8 0 0 93 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % M
% Asn: 15 0 15 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 36 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 8 8 0 0 0 % Q
% Arg: 8 0 8 0 86 15 93 0 0 0 0 0 0 93 0 % R
% Ser: 58 0 0 0 8 65 0 22 15 0 0 0 50 0 0 % S
% Thr: 0 0 8 0 0 15 0 43 0 0 0 0 15 0 0 % T
% Val: 0 0 0 93 0 0 8 8 8 0 0 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 93 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _