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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XPOT All Species: 25.76
Human Site: T99 Identified Species: 43.59
UniProt: O43592 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43592 NP_009166.2 962 109964 T99 L N P Q P E K T F I R N K A A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001116910 962 109962 T99 L N P Q P E K T F I R N K A A
Dog Lupus familis XP_531658 962 110054 T99 L N P Q P E K T F I R N K A A
Cat Felis silvestris
Mouse Mus musculus Q9CRT8 963 109715 T99 Q N P Q P E K T F I R N K A A
Rat Rattus norvegicus NP_001101572 728 83466
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508666 962 109919 T99 L N A Q P E K T F I R N K A A
Chicken Gallus gallus XP_416065 962 109808 T99 L N P Q P E K T F I R N K A A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5SPJ8 961 109329 P99 M N V H P E K P F I R N K A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_501320 950 105658 A99 S S T V D Q P A F L T N K M A
Sea Urchin Strong. purpuratus XP_786292 944 107893 S99 M A T Q E E K S F V R N K A A
Poplar Tree Populus trichocarpa XP_002304132 994 112620 A102 I D D K N N N A V R I L E G A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_177400 988 111444 R101 I D N E N A G R V V E G P P F
Baker's Yeast Sacchar. cerevisiae P33418 1100 126801 L116 I S E V L T T L F M L M Y S D
Red Bread Mold Neurospora crassa Q7RWV9 1026 114793 A101 G P N A Q D Q A D P A N V Q N
Conservation
Percent
Protein Identity: 100 N.A. 99.9 99.2 N.A. 95 68.6 N.A. 94.9 93.8 N.A. 78.4 N.A. N.A. N.A. 25.5 50.8
Protein Similarity: 100 N.A. 100 99.9 N.A. 98.2 72.2 N.A. 98.2 98.1 N.A. 89.9 N.A. N.A. N.A. 47.1 70.2
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 0 N.A. 93.3 100 N.A. 73.3 N.A. N.A. N.A. 26.6 60
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 0 N.A. 93.3 100 N.A. 80 N.A. N.A. N.A. 46.6 80
Percent
Protein Identity: 28.1 N.A. N.A. 28.5 20.2 25.8
Protein Similarity: 50.4 N.A. N.A. 50.7 42.3 45.4
P-Site Identity: 6.6 N.A. N.A. 0 6.6 6.6
P-Site Similarity: 33.3 N.A. N.A. 26.6 33.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 8 0 8 0 22 0 0 8 0 0 58 72 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 8 0 8 8 0 0 8 0 0 0 0 0 8 % D
% Glu: 0 0 8 8 8 58 0 0 0 0 8 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 72 0 0 0 0 0 8 % F
% Gly: 8 0 0 0 0 0 8 0 0 0 0 8 0 8 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 22 0 0 0 0 0 0 0 0 50 8 0 0 0 0 % I
% Lys: 0 0 0 8 0 0 58 0 0 0 0 0 65 0 0 % K
% Leu: 36 0 0 0 8 0 0 8 0 8 8 8 0 0 0 % L
% Met: 15 0 0 0 0 0 0 0 0 8 0 8 0 8 0 % M
% Asn: 0 50 15 0 15 8 8 0 0 0 0 72 0 0 8 % N
% Pro: 0 8 36 0 50 0 8 8 0 8 0 0 8 8 0 % P
% Gln: 8 0 0 50 8 8 8 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 8 0 8 58 0 0 0 0 % R
% Ser: 8 15 0 0 0 0 0 8 0 0 0 0 0 8 0 % S
% Thr: 0 0 15 0 0 8 8 43 0 0 8 0 0 0 0 % T
% Val: 0 0 8 15 0 0 0 0 15 15 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _