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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPOT
All Species:
31.21
Human Site:
Y389
Identified Species:
52.82
UniProt:
O43592
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43592
NP_009166.2
962
109964
Y389
K
L
T
Y
D
E
E
Y
N
F
E
N
E
G
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116910
962
109962
Y389
K
L
T
Y
D
E
E
Y
N
F
E
N
E
G
E
Dog
Lupus familis
XP_531658
962
110054
Y389
K
L
T
Y
D
E
E
Y
N
F
E
N
E
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CRT8
963
109715
Y390
K
L
T
Y
D
E
E
Y
N
F
E
N
E
G
E
Rat
Rattus norvegicus
NP_001101572
728
83466
I225
V
G
A
Y
V
S
W
I
D
L
S
L
I
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508666
962
109919
Y389
K
L
T
Y
D
E
E
Y
N
F
D
N
E
G
E
Chicken
Gallus gallus
XP_416065
962
109808
Y389
K
L
T
Y
D
E
E
Y
N
F
E
N
E
G
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5SPJ8
961
109329
Y389
K
L
K
Y
D
D
E
Y
N
F
E
N
E
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_501320
950
105658
M387
R
Y
V
M
N
D
D
M
T
V
G
G
D
G
E
Sea Urchin
Strong. purpuratus
XP_786292
944
107893
Y389
K
F
R
Y
D
E
T
Y
N
F
D
A
Q
G
E
Poplar Tree
Populus trichocarpa
XP_002304132
994
112620
M405
I
Y
R
E
N
L
D
M
L
D
K
I
G
R
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177400
988
111444
S401
M
Y
R
N
N
L
N
S
L
D
K
T
G
L
E
Baker's Yeast
Sacchar. cerevisiae
P33418
1100
126801
D432
F
K
R
M
K
F
S
D
D
E
V
T
Q
D
D
Red Bread Mold
Neurospora crassa
Q7RWV9
1026
114793
E423
S
W
G
T
E
D
G
E
S
D
E
A
E
F
Q
Conservation
Percent
Protein Identity:
100
N.A.
99.9
99.2
N.A.
95
68.6
N.A.
94.9
93.8
N.A.
78.4
N.A.
N.A.
N.A.
25.5
50.8
Protein Similarity:
100
N.A.
100
99.9
N.A.
98.2
72.2
N.A.
98.2
98.1
N.A.
89.9
N.A.
N.A.
N.A.
47.1
70.2
P-Site Identity:
100
N.A.
100
100
N.A.
100
6.6
N.A.
93.3
100
N.A.
86.6
N.A.
N.A.
N.A.
13.3
60
P-Site Similarity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
100
100
N.A.
93.3
N.A.
N.A.
N.A.
46.6
73.3
Percent
Protein Identity:
28.1
N.A.
N.A.
28.5
20.2
25.8
Protein Similarity:
50.4
N.A.
N.A.
50.7
42.3
45.4
P-Site Identity:
6.6
N.A.
N.A.
6.6
0
13.3
P-Site Similarity:
26.6
N.A.
N.A.
20
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
15
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
58
22
15
8
15
22
15
0
8
8
8
% D
% Glu:
0
0
0
8
8
50
50
8
0
8
50
0
58
0
79
% E
% Phe:
8
8
0
0
0
8
0
0
0
58
0
0
0
8
0
% F
% Gly:
0
8
8
0
0
0
8
0
0
0
8
8
15
65
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% I
% Lys:
58
8
8
0
8
0
0
0
0
0
15
0
0
0
0
% K
% Leu:
0
50
0
0
0
15
0
0
15
8
0
8
0
8
0
% L
% Met:
8
0
0
15
0
0
0
15
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
22
0
8
0
58
0
0
50
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
8
% Q
% Arg:
8
0
29
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
8
0
0
0
0
8
8
8
8
0
8
0
0
0
0
% S
% Thr:
0
0
43
8
0
0
8
0
8
0
0
15
0
0
0
% T
% Val:
8
0
8
0
8
0
0
0
0
8
8
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
22
0
65
0
0
0
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _