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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HR
All Species:
16.06
Human Site:
S538
Identified Species:
44.17
UniProt:
O43593
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43593
NP_005135.2
1189
127495
S538
D
T
A
T
N
S
S
S
E
E
G
P
G
S
G
Chimpanzee
Pan troglodytes
XP_519644
1189
127418
S538
D
T
A
A
N
S
S
S
E
E
G
P
G
S
G
Rhesus Macaque
Macaca mulatta
NP_001028015
1187
127116
S536
D
T
A
A
N
S
S
S
E
E
G
P
G
S
G
Dog
Lupus familis
XP_543256
1209
129846
S560
E
E
D
S
A
A
S
S
E
E
G
G
G
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61645
1182
127174
E533
E
D
S
S
A
T
S
E
E
G
G
G
G
P
G
Rat
Rattus norvegicus
P97609
1181
127289
S532
E
E
D
S
C
A
T
S
E
E
G
G
G
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511537
1285
142386
S566
K
Y
D
L
E
A
I
S
L
W
L
P
V
A
K
Chicken
Gallus gallus
Q5ZIX8
1325
149315
P604
L
T
P
N
K
Y
D
P
E
A
I
S
L
W
L
Frog
Xenopus laevis
Q5HZN1
1334
149927
N623
K
Y
D
A
E
A
I
N
L
W
L
P
L
A
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.2
82.3
N.A.
79.6
78.9
N.A.
22.1
22.2
21.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
97.1
86.7
N.A.
85.4
84.9
N.A.
37
37.5
35.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
53.3
N.A.
33.3
40
N.A.
13.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
73.3
N.A.
60
66.6
N.A.
26.6
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
34
23
45
0
0
0
12
0
0
0
23
0
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
12
45
0
0
0
12
0
0
0
0
0
0
0
0
% D
% Glu:
34
23
0
0
23
0
0
12
78
56
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
12
67
34
67
0
56
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
23
0
0
0
12
0
0
0
0
% I
% Lys:
23
0
0
0
12
0
0
0
0
0
0
0
0
0
12
% K
% Leu:
12
0
0
12
0
0
0
0
23
0
23
0
23
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
34
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
0
0
0
0
12
0
0
0
56
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
12
34
0
34
56
67
0
0
0
12
0
56
23
% S
% Thr:
0
45
0
12
0
12
12
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
23
0
0
0
12
0
% W
% Tyr:
0
23
0
0
0
12
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _