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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RCL All Species: 11.82
Human Site: S28 Identified Species: 37.14
UniProt: O43598 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43598 NP_006434.1 174 19108 S28 P A L Y F C G S I R G G R E D
Chimpanzee Pan troglodytes XP_518907 121 13295
Rhesus Macaque Macaca mulatta XP_001093715 174 19061 S28 P A L Y F C G S I R G G R E D
Dog Lupus familis XP_538931 165 17954 S30 R A L Y F C G S V R G G R E D
Cat Felis silvestris
Mouse Mus musculus Q80VJ3 173 18959 V41 R L R R Y G K V L T E H V A D
Rat Rattus norvegicus O35820 163 17762 V41 R L R R Y G K V L T E H V A D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio B8A556 143 16168 L26 Y Q T I V K K L Q Q Y G N V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195603 127 14003 S13 L K I Y F G R S I R G G Q K G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.5 94.2 78.7 N.A. 73.5 74.1 N.A. N.A. N.A. N.A. 51.1 N.A. N.A. N.A. N.A. 34.4
Protein Similarity: 100 68.3 95.9 84.4 N.A. 79.8 79.8 N.A. N.A. N.A. N.A. 65.5 N.A. N.A. N.A. N.A. 48.8
P-Site Identity: 100 0 100 86.6 N.A. 6.6 6.6 N.A. N.A. N.A. N.A. 6.6 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 0 100 93.3 N.A. 20 20 N.A. N.A. N.A. N.A. 13.3 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 38 0 0 0 0 0 0 0 0 0 0 0 25 0 % A
% Cys: 0 0 0 0 0 38 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 63 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 25 0 0 38 0 % E
% Phe: 0 0 0 0 50 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 38 38 0 0 0 50 63 0 0 13 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 % H
% Ile: 0 0 13 13 0 0 0 0 38 0 0 0 0 0 0 % I
% Lys: 0 13 0 0 0 13 38 0 0 0 0 0 0 13 0 % K
% Leu: 13 25 38 0 0 0 0 13 25 0 0 0 0 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % N
% Pro: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 13 0 0 0 0 0 0 13 13 0 0 13 0 0 % Q
% Arg: 38 0 25 25 0 0 13 0 0 50 0 0 38 0 0 % R
% Ser: 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % S
% Thr: 0 0 13 0 0 0 0 0 0 25 0 0 0 0 0 % T
% Val: 0 0 0 0 13 0 0 25 13 0 0 0 25 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 0 0 50 25 0 0 0 0 0 13 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _