KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCRT
All Species:
4.55
Human Site:
T65
Identified Species:
16.67
UniProt:
O43612
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43612
NP_001515.1
131
13363
T65
N
H
A
A
G
I
L
T
L
G
K
R
R
S
G
Chimpanzee
Pan troglodytes
XP_001166578
130
13257
L65
H
A
A
G
I
L
T
L
G
K
R
R
S
G
P
Rhesus Macaque
Macaca mulatta
XP_001108991
131
13365
T65
N
H
A
A
G
I
L
T
L
G
K
R
R
S
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O55241
130
13484
L65
H
A
A
G
I
L
T
L
G
K
R
R
P
G
P
Rat
Rattus norvegicus
O55232
130
13627
L65
H
A
A
G
I
L
T
L
G
K
R
R
P
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989516
148
15882
K65
I
L
T
L
G
K
R
K
S
I
P
P
A
F
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070860
129
14217
D65
H
L
V
H
L
N
N
D
A
A
V
G
I
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
95.4
N.A.
N.A.
81.6
83.2
N.A.
N.A.
51.3
N.A.
33.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
95.4
N.A.
N.A.
84.7
86.2
N.A.
N.A.
62.1
N.A.
46.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
N.A.
N.A.
13.3
13.3
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
N.A.
N.A.
33.3
33.3
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
43
72
29
0
0
0
0
15
15
0
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% F
% Gly:
0
0
0
43
43
0
0
0
43
29
0
15
0
43
29
% G
% His:
58
29
0
15
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
0
0
0
43
29
0
0
0
15
0
0
15
0
0
% I
% Lys:
0
0
0
0
0
15
0
15
0
43
29
0
0
0
0
% K
% Leu:
0
29
0
15
15
43
29
43
29
0
0
0
0
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
29
0
0
0
0
15
15
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
15
15
29
0
43
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% Q
% Arg:
0
0
0
0
0
0
15
0
0
0
43
72
29
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
15
0
0
0
15
29
0
% S
% Thr:
0
0
15
0
0
0
43
29
0
0
0
0
0
0
15
% T
% Val:
0
0
15
0
0
0
0
0
0
0
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _