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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HCRTR1 All Species: 9.39
Human Site: S21 Identified Species: 17.22
UniProt: O43613 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43613 NP_001516.2 425 47536 S21 P P G S R E P S P V P P D Y E
Chimpanzee Pan troglodytes XP_524646 425 47381 S21 P P G S R E P S P V P P D Y E
Rhesus Macaque Macaca mulatta Q9GK74 381 42711
Dog Lupus familis XP_544446 502 56267 S98 G G G E L S P S L V P P D Y E
Cat Felis silvestris
Mouse Mus musculus P58307 416 46748 F21 P T S S G E P F H L P P D Y E
Rat Rattus norvegicus P56718 416 46781 F21 P T S S G E P F H L P P D Y E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507023 412 46359 P18 T P R A P G G P F S P D D Y D
Chicken Gallus gallus Q9DDN6 385 43491
Frog Xenopus laevis P70031 453 51139 A43 G T H N L T T A N W P P W N L
Zebra Danio Brachydanio rerio NP_001073337 424 48183 H29 S S A D T I S H S H A E N E D
Tiger Blowfish Takifugu rubipres NP_001092118 426 48303 S24 T F Y N S T E S V P P R N N I
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120335 399 45437
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789606 462 52471 S30 N L S T N S S S S L Y Y G E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 25.8 78.8 N.A. 91.7 91.5 N.A. 81.8 26.5 24.5 61.1 26 N.A. 35.7 N.A. 32.9
Protein Similarity: 100 96.4 46.3 81 N.A. 93.8 93.6 N.A. 85.6 47.5 47.4 73.1 42.9 N.A. 51.7 N.A. 51.5
P-Site Identity: 100 100 0 60 N.A. 60 60 N.A. 26.6 0 13.3 0 13.3 N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 0 60 N.A. 66.6 66.6 N.A. 40 0 26.6 13.3 26.6 N.A. 0 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 0 0 8 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 0 8 47 0 16 % D
% Glu: 0 0 0 8 0 31 8 0 0 0 0 8 0 16 39 % E
% Phe: 0 8 0 0 0 0 0 16 8 0 0 0 0 0 0 % F
% Gly: 16 8 24 0 16 8 8 0 0 0 0 0 8 0 0 % G
% His: 0 0 8 0 0 0 0 8 16 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 0 0 16 0 0 0 8 24 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 16 8 0 0 0 8 0 0 0 16 16 0 % N
% Pro: 31 24 0 0 8 0 39 8 16 8 62 47 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 16 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 8 8 24 31 8 16 16 39 16 8 0 0 0 0 8 % S
% Thr: 16 24 0 8 8 16 8 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 8 24 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 8 8 0 47 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _