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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCRTR1
All Species:
10.91
Human Site:
S273
Identified Species:
20
UniProt:
O43613
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43613
NP_001516.2
425
47536
S273
G
D
L
E
Q
G
L
S
G
E
P
Q
P
R
A
Chimpanzee
Pan troglodytes
XP_524646
425
47381
S273
G
D
L
E
Q
G
L
S
G
E
P
Q
P
R
A
Rhesus Macaque
Macaca mulatta
Q9GK74
381
42711
Y239
L
G
I
I
S
F
S
Y
T
R
I
W
S
K
L
Dog
Lupus familis
XP_544446
502
56267
S350
E
D
Q
G
P
G
L
S
A
E
P
P
P
R
A
Cat
Felis silvestris
Mouse
Mus musculus
P58307
416
46748
C273
E
A
Q
H
Q
G
L
C
T
E
P
Q
P
R
A
Rat
Rattus norvegicus
P56718
416
46781
C273
E
A
Q
H
Q
G
L
C
T
E
P
Q
P
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507023
412
46359
R270
P
G
P
P
A
P
A
R
A
S
A
F
L
A
E
Chicken
Gallus gallus
Q9DDN6
385
43491
Y243
L
A
I
I
S
Y
A
Y
T
R
I
W
T
K
L
Frog
Xenopus laevis
P70031
453
51139
E295
T
T
I
P
S
G
D
E
G
D
G
C
Y
I
Q
Zebra Danio
Brachydanio rerio
NP_001073337
424
48183
S281
H
A
V
G
S
G
E
S
V
K
V
R
T
S
T
Tiger Blowfish
Takifugu rubipres
NP_001092118
426
48303
L276
Q
R
V
I
K
M
L
L
I
V
A
L
L
F
I
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120335
399
45437
F257
S
K
K
N
Q
V
I
F
I
I
V
K
L
I
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789606
462
52471
S282
R
H
H
S
N
G
K
S
I
S
T
G
K
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
25.8
78.8
N.A.
91.7
91.5
N.A.
81.8
26.5
24.5
61.1
26
N.A.
35.7
N.A.
32.9
Protein Similarity:
100
96.4
46.3
81
N.A.
93.8
93.6
N.A.
85.6
47.5
47.4
73.1
42.9
N.A.
51.7
N.A.
51.5
P-Site Identity:
100
100
0
60
N.A.
60
60
N.A.
0
0
13.3
13.3
6.6
N.A.
6.6
N.A.
20
P-Site Similarity:
100
100
13.3
60
N.A.
60
60
N.A.
0
13.3
26.6
33.3
20
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
0
0
8
0
16
0
16
0
16
0
0
8
47
% A
% Cys:
0
0
0
0
0
0
0
16
0
0
0
8
0
0
0
% C
% Asp:
0
24
0
0
0
0
8
0
0
8
0
0
0
0
0
% D
% Glu:
24
0
0
16
0
0
8
8
0
39
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
8
0
8
0
0
0
8
0
8
8
% F
% Gly:
16
16
0
16
0
62
0
0
24
0
8
8
0
8
0
% G
% His:
8
8
8
16
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
24
24
0
0
8
0
24
8
16
0
0
16
8
% I
% Lys:
0
8
8
0
8
0
8
0
0
8
0
8
8
16
0
% K
% Leu:
16
0
16
0
0
0
47
8
0
0
0
8
24
0
16
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
8
16
8
8
0
0
0
0
39
8
39
0
0
% P
% Gln:
8
0
24
0
39
0
0
0
0
0
0
31
0
0
8
% Q
% Arg:
8
8
0
0
0
0
0
8
0
16
0
8
0
39
0
% R
% Ser:
8
0
0
8
31
0
8
39
0
16
0
0
8
8
0
% S
% Thr:
8
8
0
0
0
0
0
0
31
0
8
0
16
0
8
% T
% Val:
0
0
16
0
0
8
0
0
8
8
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
16
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _