KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCRTR1
All Species:
10.61
Human Site:
S331
Identified Species:
19.44
UniProt:
O43613
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43613
NP_001516.2
425
47536
S331
F
G
M
F
R
Q
A
S
D
R
E
A
V
Y
A
Chimpanzee
Pan troglodytes
XP_524646
425
47381
S331
F
G
M
F
R
Q
A
S
D
R
E
A
V
Y
A
Rhesus Macaque
Macaca mulatta
Q9GK74
381
42711
Q288
W
L
P
L
H
A
F
Q
L
A
V
D
I
D
S
Dog
Lupus familis
XP_544446
502
56267
S408
F
G
M
F
R
Q
S
S
D
R
E
A
V
Y
T
Cat
Felis silvestris
Mouse
Mus musculus
P58307
416
46748
R322
S
V
L
N
V
L
K
R
V
F
G
M
F
R
Q
Rat
Rattus norvegicus
P56718
416
46781
R322
S
V
L
N
V
L
K
R
V
F
G
M
F
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507023
412
46359
A319
K
R
V
F
G
M
F
A
N
T
S
D
R
E
S
Chicken
Gallus gallus
Q9DDN6
385
43491
Q292
W
L
P
F
H
A
F
Q
L
V
S
D
I
D
S
Frog
Xenopus laevis
P70031
453
51139
F352
L
I
V
I
V
A
M
F
F
I
C
W
M
P
I
Zebra Danio
Brachydanio rerio
NP_001073337
424
48183
G331
N
I
M
K
R
V
F
G
A
F
K
N
T
G
N
Tiger Blowfish
Takifugu rubipres
NP_001092118
426
48303
S326
W
L
A
F
F
N
S
S
V
N
P
I
I
Y
G
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120335
399
45437
P306
S
Q
M
S
Q
I
P
P
S
G
G
G
N
P
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789606
462
52471
G354
M
N
L
K
S
E
L
G
D
R
S
K
V
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
25.8
78.8
N.A.
91.7
91.5
N.A.
81.8
26.5
24.5
61.1
26
N.A.
35.7
N.A.
32.9
Protein Similarity:
100
96.4
46.3
81
N.A.
93.8
93.6
N.A.
85.6
47.5
47.4
73.1
42.9
N.A.
51.7
N.A.
51.5
P-Site Identity:
100
100
0
86.6
N.A.
0
0
N.A.
6.6
6.6
0
13.3
20
N.A.
6.6
N.A.
20
P-Site Similarity:
100
100
20
93.3
N.A.
6.6
6.6
N.A.
33.3
26.6
13.3
20
40
N.A.
13.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
24
16
8
8
8
0
24
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
31
0
0
24
0
16
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
24
0
0
8
8
% E
% Phe:
24
0
0
47
8
0
31
8
8
24
0
0
16
0
0
% F
% Gly:
0
24
0
0
8
0
0
16
0
8
24
8
0
8
8
% G
% His:
0
0
0
0
16
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
16
0
8
0
8
0
0
0
8
0
8
24
0
8
% I
% Lys:
8
0
0
16
0
0
16
0
0
0
8
8
0
0
0
% K
% Leu:
8
24
24
8
0
16
8
0
16
0
0
0
0
0
8
% L
% Met:
8
0
39
0
0
8
8
0
0
0
0
16
8
0
0
% M
% Asn:
8
8
0
16
0
8
0
0
8
8
0
8
8
0
8
% N
% Pro:
0
0
16
0
0
0
8
8
0
0
8
0
0
16
0
% P
% Gln:
0
8
0
0
8
24
0
16
0
0
0
0
0
0
16
% Q
% Arg:
0
8
0
0
31
0
0
16
0
31
0
0
8
16
0
% R
% Ser:
24
0
0
8
8
0
16
31
8
0
24
0
0
0
24
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
8
% T
% Val:
0
16
16
0
24
8
0
0
24
8
8
0
31
0
0
% V
% Trp:
24
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
31
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _