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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HCRTR1 All Species: 12.42
Human Site: S385 Identified Species: 22.78
UniProt: O43613 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43613 NP_001516.2 425 47536 S385 P G L G P C G S L K A P S P R
Chimpanzee Pan troglodytes XP_524646 425 47381 S385 P G L G P C G S L K A P S P R
Rhesus Macaque Macaca mulatta Q9GK74 381 42711 C342 A F L S A F R C E Q R L D A I
Dog Lupus familis XP_544446 502 56267 S462 P G L G P C G S P K A P S P R
Cat Felis silvestris
Mouse Mus musculus P58307 416 46748 C376 F K A A F S C C L P G L G P G
Rat Rattus norvegicus P56718 416 46781 C376 F K A A F S C C L P G L G P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507023 412 46359 S373 C C L P T F G S F Q T P S S R
Chicken Gallus gallus Q9DDN6 385 43491 C346 A F L T A F Q C E Q R L D S I
Frog Xenopus laevis P70031 453 51139 R406 I Y C F M N K R F R K A F L G
Zebra Danio Brachydanio rerio NP_001073337 424 48183 G385 A F I C Q C S G R G E T H K Q
Tiger Blowfish Takifugu rubipres NP_001092118 426 48303 S380 P A N N A Q T S L E P I S L N
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120335 399 45437 A360 P S N K W I N A I S L I A H G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789606 462 52471 A408 R T A F G T C A C C P Q P T R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 25.8 78.8 N.A. 91.7 91.5 N.A. 81.8 26.5 24.5 61.1 26 N.A. 35.7 N.A. 32.9
Protein Similarity: 100 96.4 46.3 81 N.A. 93.8 93.6 N.A. 85.6 47.5 47.4 73.1 42.9 N.A. 51.7 N.A. 51.5
P-Site Identity: 100 100 6.6 93.3 N.A. 13.3 13.3 N.A. 40 6.6 0 6.6 26.6 N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 100 13.3 93.3 N.A. 13.3 13.3 N.A. 46.6 13.3 6.6 20 33.3 N.A. 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 8 24 16 24 0 0 16 0 0 24 8 8 8 0 % A
% Cys: 8 8 8 8 0 31 24 31 8 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 16 8 8 0 0 0 0 % E
% Phe: 16 24 0 16 16 24 0 0 16 0 0 0 8 0 0 % F
% Gly: 0 24 0 24 8 0 31 8 0 8 16 0 16 0 24 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % H
% Ile: 8 0 8 0 0 8 0 0 8 0 0 16 0 0 16 % I
% Lys: 0 16 0 8 0 0 8 0 0 24 8 0 0 8 0 % K
% Leu: 0 0 47 0 0 0 0 0 39 0 8 31 0 16 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 16 8 0 8 8 0 0 0 0 0 0 0 8 % N
% Pro: 39 0 0 8 24 0 0 0 8 16 16 31 8 39 0 % P
% Gln: 0 0 0 0 8 8 8 0 0 24 0 8 0 0 8 % Q
% Arg: 8 0 0 0 0 0 8 8 8 8 16 0 0 0 39 % R
% Ser: 0 8 0 8 0 16 8 39 0 8 0 0 39 16 8 % S
% Thr: 0 8 0 8 8 8 8 0 0 0 8 8 0 8 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _