Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HCRTR1 All Species: 13.03
Human Site: S390 Identified Species: 23.89
UniProt: O43613 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43613 NP_001516.2 425 47536 S390 C G S L K A P S P R S S A S H
Chimpanzee Pan troglodytes XP_524646 425 47381 S390 C G S L K A P S P R S S A S H
Rhesus Macaque Macaca mulatta Q9GK74 381 42711 D347 F R C E Q R L D A I H S E V S
Dog Lupus familis XP_544446 502 56267 S467 C G S P K A P S P R S S A S H
Cat Felis silvestris
Mouse Mus musculus P58307 416 46748 G381 S C C L P G L G P G S S A R H
Rat Rattus norvegicus P56718 416 46781 G381 S C C L P G L G P S S S A R H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507023 412 46359 S378 F G S F Q T P S S R S T S Q K
Chicken Gallus gallus Q9DDN6 385 43491 D351 F Q C E Q R L D S I H P E V S
Frog Xenopus laevis P70031 453 51139 F411 N K R F R K A F L G T F S S C
Zebra Danio Brachydanio rerio NP_001073337 424 48183 H390 C S G R G E T H K Q R A R G R
Tiger Blowfish Takifugu rubipres NP_001092118 426 48303 S385 Q T S L E P I S L N S L D R K
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120335 399 45437 A365 I N A I S L I A H G L C Y F N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789606 462 52471 P413 T C A C C P Q P T R D S T A I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 25.8 78.8 N.A. 91.7 91.5 N.A. 81.8 26.5 24.5 61.1 26 N.A. 35.7 N.A. 32.9
Protein Similarity: 100 96.4 46.3 81 N.A. 93.8 93.6 N.A. 85.6 47.5 47.4 73.1 42.9 N.A. 51.7 N.A. 51.5
P-Site Identity: 100 100 6.6 93.3 N.A. 40 40 N.A. 40 0 6.6 6.6 26.6 N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 13.3 93.3 N.A. 40 40 N.A. 60 6.6 26.6 20 33.3 N.A. 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 0 0 24 8 8 8 0 0 8 39 8 0 % A
% Cys: 31 24 31 8 8 0 0 0 0 0 0 8 0 0 8 % C
% Asp: 0 0 0 0 0 0 0 16 0 0 8 0 8 0 0 % D
% Glu: 0 0 0 16 8 8 0 0 0 0 0 0 16 0 0 % E
% Phe: 24 0 0 16 0 0 0 8 0 0 0 8 0 8 0 % F
% Gly: 0 31 8 0 8 16 0 16 0 24 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 8 8 0 16 0 0 0 39 % H
% Ile: 8 0 0 8 0 0 16 0 0 16 0 0 0 0 8 % I
% Lys: 0 8 0 0 24 8 0 0 8 0 0 0 0 0 16 % K
% Leu: 0 0 0 39 0 8 31 0 16 0 8 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 8 0 0 0 0 0 0 0 8 0 0 0 0 8 % N
% Pro: 0 0 0 8 16 16 31 8 39 0 0 8 0 0 0 % P
% Gln: 8 8 0 0 24 0 8 0 0 8 0 0 0 8 0 % Q
% Arg: 0 8 8 8 8 16 0 0 0 39 8 0 8 24 8 % R
% Ser: 16 8 39 0 8 0 0 39 16 8 54 54 16 31 16 % S
% Thr: 8 8 0 0 0 8 8 0 8 0 8 8 8 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _