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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HCRTR1 All Species: 13.85
Human Site: T6 Identified Species: 25.38
UniProt: O43613 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43613 NP_001516.2 425 47536 T6 _ _ M E P S A T P G A Q M G V
Chimpanzee Pan troglodytes XP_524646 425 47381 T6 _ _ M E P S A T P G A Q M G V
Rhesus Macaque Macaca mulatta Q9GK74 381 42711
Dog Lupus familis XP_544446 502 56267 G83 M E P S A T P G A Q T G T P T
Cat Felis silvestris
Mouse Mus musculus P58307 416 46748 T6 _ _ M E P S A T P G A Q P G V
Rat Rattus norvegicus P56718 416 46781 T6 _ _ M E P S A T P G A Q P G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507023 412 46359
Chicken Gallus gallus Q9DDN6 385 43491
Frog Xenopus laevis P70031 453 51139 T28 S N L S G T L T W N L S S T N
Zebra Danio Brachydanio rerio NP_001073337 424 48183 F14 Q R A C N S C F T S A Q H L N
Tiger Blowfish Takifugu rubipres NP_001092118 426 48303 L9 S K D L E S N L T Q M Y D N W
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120335 399 45437
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789606 462 52471 D15 D N L T D I G D E I Y A S A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 25.8 78.8 N.A. 91.7 91.5 N.A. 81.8 26.5 24.5 61.1 26 N.A. 35.7 N.A. 32.9
Protein Similarity: 100 96.4 46.3 81 N.A. 93.8 93.6 N.A. 85.6 47.5 47.4 73.1 42.9 N.A. 51.7 N.A. 51.5
P-Site Identity: 100 100 0 0 N.A. 92.3 92.3 N.A. 0 0 6.6 20 6.6 N.A. 0 N.A. 0
P-Site Similarity: 100 100 0 6.6 N.A. 92.3 92.3 N.A. 0 0 20 20 6.6 N.A. 0 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 8 0 31 0 8 0 39 8 0 8 8 % A
% Cys: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 8 0 0 8 0 0 0 0 8 0 0 % D
% Glu: 0 8 0 31 8 0 0 0 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 8 8 0 31 0 8 0 31 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 16 8 0 0 8 8 0 0 8 0 0 8 0 % L
% Met: 8 0 31 0 0 0 0 0 0 0 8 0 16 0 0 % M
% Asn: 0 16 0 0 8 0 8 0 0 8 0 0 0 8 16 % N
% Pro: 0 0 8 0 31 0 8 0 31 0 0 0 16 8 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 16 0 39 0 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 16 0 0 16 0 47 0 0 0 8 0 8 16 0 0 % S
% Thr: 0 0 0 8 0 16 0 39 16 0 8 0 8 8 8 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % Y
% Spaces: 31 31 0 0 0 0 0 0 0 0 0 0 0 0 0 % _