Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HCRTR1 All Species: 36.06
Human Site: Y83 Identified Species: 66.11
UniProt: O43613 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43613 NP_001516.2 425 47536 Y83 H M R T V T N Y F I V N L S L
Chimpanzee Pan troglodytes XP_524646 425 47381 Y83 H M R T V T N Y F I V N L S L
Rhesus Macaque Macaca mulatta Q9GK74 381 42711 V49 D S T K L I E V Q V V L I L A
Dog Lupus familis XP_544446 502 56267 Y160 H M R T V T N Y F I V N L S L
Cat Felis silvestris
Mouse Mus musculus P58307 416 46748 Y83 H M R T V T N Y F I V N L S L
Rat Rattus norvegicus P56718 416 46781 Y83 H M R T V T N Y F I V N L S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507023 412 46359 Y80 H M R S V T N Y F I V N L S L
Chicken Gallus gallus Q9DDN6 385 43491 V53 D S T T L V E V Q I I L I F A
Frog Xenopus laevis P70031 453 51139 S105 R L R T I T N S F L L S L A L
Zebra Danio Brachydanio rerio NP_001073337 424 48183 Y91 H M R T V T N Y F I V N L S F
Tiger Blowfish Takifugu rubipres NP_001092118 426 48303 L86 T N L F I L N L A V S D L L V
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120335 399 45437 S67 W D W V L I A S H S I V F V I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789606 462 52471 Y92 H M R S V T N Y Y I V N L S A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 25.8 78.8 N.A. 91.7 91.5 N.A. 81.8 26.5 24.5 61.1 26 N.A. 35.7 N.A. 32.9
Protein Similarity: 100 96.4 46.3 81 N.A. 93.8 93.6 N.A. 85.6 47.5 47.4 73.1 42.9 N.A. 51.7 N.A. 51.5
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 93.3 13.3 46.6 93.3 13.3 N.A. 0 N.A. 80
P-Site Similarity: 100 100 26.6 100 N.A. 100 100 N.A. 100 33.3 86.6 93.3 40 N.A. 20 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 8 0 0 0 0 8 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 0 0 0 0 0 16 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 62 0 0 0 8 8 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 62 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 16 16 0 0 0 70 16 0 16 0 8 % I
% Lys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 8 0 24 8 0 8 0 8 8 16 77 16 54 % L
% Met: 0 62 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 77 0 0 0 0 62 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 % Q
% Arg: 8 0 70 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 16 0 16 0 0 0 16 0 8 8 8 0 62 0 % S
% Thr: 8 0 16 62 0 70 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 8 62 8 0 16 0 16 70 8 0 8 8 % V
% Trp: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 62 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _