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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCRTR2
All Species:
13.64
Human Site:
S260
Identified Species:
25
UniProt:
O43614
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43614
NP_001517.2
444
50694
S260
R
Q
I
P
G
T
S
S
V
V
Q
R
K
W
K
Chimpanzee
Pan troglodytes
XP_518552
444
50692
S260
R
Q
I
P
G
T
S
S
V
V
Q
R
K
W
K
Rhesus Macaque
Macaca mulatta
Q9GK74
381
42711
A202
I
P
D
F
E
I
V
A
C
T
E
K
W
P
G
Dog
Lupus familis
XP_544446
502
56267
G321
Q
I
F
R
K
L
W
G
R
Q
I
P
G
T
T
Cat
Felis silvestris
Mouse
Mus musculus
P58308
460
52443
S260
R
Q
I
P
G
T
S
S
V
V
Q
R
K
W
K
Rat
Rattus norvegicus
P56719
460
52471
S260
R
Q
I
P
G
T
S
S
V
V
Q
R
K
W
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507023
412
46359
Q234
L
M
F
M
A
Y
F
Q
I
F
R
K
L
W
G
Chicken
Gallus gallus
Q9DDN6
385
43491
C207
P
D
F
K
I
V
V
C
S
E
K
W
P
G
E
Frog
Xenopus laevis
P70031
453
51139
N274
I
Q
F
E
M
D
L
N
K
E
A
K
A
H
K
Zebra Danio
Brachydanio rerio
NP_001073337
424
48183
I246
M
V
L
A
Y
I
Q
I
C
H
K
L
W
C
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25931
464
53506
F279
Y
Y
Y
T
L
S
L
F
A
L
Q
F
V
V
P
Honey Bee
Apis mellifera
XP_001120335
399
45437
I221
T
L
N
V
C
A
D
I
P
D
L
V
V
L
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789606
462
52471
E261
W
S
A
I
P
G
E
E
T
R
R
K
K
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
28.3
58.7
N.A.
91
91
N.A.
66.8
26.7
21.6
67.7
N.A.
29
30.4
N.A.
34.4
Protein Similarity:
100
99.7
45
69.5
N.A.
93.2
93
N.A.
78.5
44.1
40.8
81.3
N.A.
46.1
46.6
N.A.
53.6
P-Site Identity:
100
100
0
0
N.A.
100
100
N.A.
6.6
0
13.3
0
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
100
20
6.6
N.A.
100
100
N.A.
26.6
13.3
26.6
20
N.A.
20
0
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
8
0
8
8
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
8
0
0
8
16
0
0
0
0
8
0
% C
% Asp:
0
8
8
0
0
8
8
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
8
8
0
8
8
0
16
8
0
0
0
8
% E
% Phe:
0
0
31
8
0
0
8
8
0
8
0
8
0
0
0
% F
% Gly:
0
0
0
0
31
8
0
8
0
0
0
0
8
8
16
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% H
% Ile:
16
8
31
8
8
16
0
16
8
0
8
0
0
0
0
% I
% Lys:
0
0
0
8
8
0
0
0
8
0
16
31
39
0
39
% K
% Leu:
8
8
8
0
8
8
16
0
0
8
8
8
8
8
0
% L
% Met:
8
8
0
8
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% N
% Pro:
8
8
0
31
8
0
0
0
8
0
0
8
8
16
8
% P
% Gln:
8
39
0
0
0
0
8
8
0
8
39
0
0
0
8
% Q
% Arg:
31
0
0
8
0
0
0
0
8
8
16
31
0
0
0
% R
% Ser:
0
8
0
0
0
8
31
31
8
0
0
0
0
0
0
% S
% Thr:
8
0
0
8
0
31
0
0
8
8
0
0
0
8
8
% T
% Val:
0
8
0
8
0
8
16
0
31
31
0
8
16
8
0
% V
% Trp:
8
0
0
0
0
0
8
0
0
0
0
8
16
39
0
% W
% Tyr:
8
8
8
0
8
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _