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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCRTR2
All Species:
14.24
Human Site:
S273
Identified Species:
26.11
UniProt:
O43614
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43614
NP_001517.2
444
50694
S273
W
K
P
L
Q
P
V
S
Q
P
R
G
P
G
Q
Chimpanzee
Pan troglodytes
XP_518552
444
50692
S273
W
K
P
L
Q
P
V
S
Q
P
R
G
P
G
Q
Rhesus Macaque
Macaca mulatta
Q9GK74
381
42711
Y215
P
G
E
E
K
S
I
Y
G
T
V
Y
S
L
S
Dog
Lupus familis
XP_544446
502
56267
N334
T
T
S
A
L
V
R
N
W
K
R
P
S
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
P58308
460
52443
S273
W
K
Q
Q
Q
P
V
S
Q
P
R
G
S
G
Q
Rat
Rattus norvegicus
P56719
460
52471
S273
W
K
Q
P
Q
P
V
S
Q
P
R
G
S
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507023
412
46359
T247
W
G
R
Q
I
P
G
T
T
S
A
L
V
R
N
Chicken
Gallus gallus
Q9DDN6
385
43491
G220
G
E
G
Q
L
N
Y
G
T
I
Y
S
V
S
M
Frog
Xenopus laevis
P70031
453
51139
P287
H
K
N
G
V
S
T
P
T
T
I
P
S
G
D
Zebra Danio
Brachydanio rerio
NP_001073337
424
48183
S259
C
Q
Q
I
P
G
S
S
S
V
L
Q
R
Q
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25931
464
53506
F292
V
P
L
G
V
L
I
F
T
Y
A
R
I
T
I
Honey Bee
Apis mellifera
XP_001120335
399
45437
H234
L
H
T
V
P
P
T
H
I
K
I
K
T
I
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789606
462
52471
A274
P
N
D
S
N
N
E
A
R
H
H
S
N
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
28.3
58.7
N.A.
91
91
N.A.
66.8
26.7
21.6
67.7
N.A.
29
30.4
N.A.
34.4
Protein Similarity:
100
99.7
45
69.5
N.A.
93.2
93
N.A.
78.5
44.1
40.8
81.3
N.A.
46.1
46.6
N.A.
53.6
P-Site Identity:
100
100
0
13.3
N.A.
80
80
N.A.
13.3
0
13.3
6.6
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
13.3
20
N.A.
80
80
N.A.
20
6.6
13.3
20
N.A.
6.6
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
8
0
0
16
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
8
% D
% Glu:
0
8
8
8
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
16
8
16
0
8
8
8
8
0
0
31
0
47
0
% G
% His:
8
8
0
0
0
0
0
8
0
8
8
0
0
0
0
% H
% Ile:
0
0
0
8
8
0
16
0
8
8
16
0
8
8
8
% I
% Lys:
0
39
0
0
8
0
0
0
0
16
0
8
0
0
8
% K
% Leu:
8
0
8
16
16
8
0
0
0
0
8
8
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
8
0
8
16
0
8
0
0
0
0
8
0
8
% N
% Pro:
16
8
16
8
16
47
0
8
0
31
0
16
16
0
0
% P
% Gln:
0
8
24
24
31
0
0
0
31
0
0
8
0
8
39
% Q
% Arg:
0
0
8
0
0
0
8
0
8
0
39
8
8
8
0
% R
% Ser:
0
0
8
8
0
16
8
39
8
8
0
16
39
8
8
% S
% Thr:
8
8
8
0
0
0
16
8
31
16
0
0
8
8
0
% T
% Val:
8
0
0
8
16
8
31
0
0
8
8
0
16
0
0
% V
% Trp:
39
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
8
8
0
8
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _