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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCRTR2
All Species:
11.82
Human Site:
S412
Identified Species:
21.67
UniProt:
O43614
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43614
NP_001517.2
444
50694
S412
K
S
L
T
T
Q
I
S
N
F
D
N
I
S
K
Chimpanzee
Pan troglodytes
XP_518552
444
50692
S412
K
S
L
T
T
Q
I
S
N
F
D
N
I
S
K
Rhesus Macaque
Macaca mulatta
Q9GK74
381
42711
S354
D
A
I
H
S
E
V
S
V
T
F
K
A
K
K
Dog
Lupus familis
XP_544446
502
56267
S473
P
S
P
R
S
S
A
S
H
K
S
L
S
L
H
Cat
Felis silvestris
Mouse
Mus musculus
P58308
460
52443
N412
S
L
T
T
Q
I
S
N
F
D
N
V
S
K
L
Rat
Rattus norvegicus
P56719
460
52471
N412
S
L
T
T
Q
I
S
N
F
D
N
V
S
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507023
412
46359
S386
S
R
S
T
S
Q
K
S
L
S
L
Q
S
K
F
Chicken
Gallus gallus
Q9DDN6
385
43491
A359
S
I
H
P
E
V
S
A
A
F
K
A
R
K
K
Frog
Xenopus laevis
P70031
453
51139
R426
I
K
P
C
R
N
F
R
D
T
D
E
D
I
A
Zebra Danio
Brachydanio rerio
NP_001073337
424
48183
T398
K
Q
R
A
R
G
R
T
S
T
D
S
R
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25931
464
53506
R431
G
P
A
L
P
L
N
R
M
N
T
S
T
T
Y
Honey Bee
Apis mellifera
XP_001120335
399
45437
S373
H
G
L
C
Y
F
N
S
A
V
N
P
L
I
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789606
462
52471
P413
T
C
A
C
C
P
Q
P
T
R
D
S
T
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
28.3
58.7
N.A.
91
91
N.A.
66.8
26.7
21.6
67.7
N.A.
29
30.4
N.A.
34.4
Protein Similarity:
100
99.7
45
69.5
N.A.
93.2
93
N.A.
78.5
44.1
40.8
81.3
N.A.
46.1
46.6
N.A.
53.6
P-Site Identity:
100
100
13.3
13.3
N.A.
6.6
6.6
N.A.
20
13.3
6.6
13.3
N.A.
0
13.3
N.A.
6.6
P-Site Similarity:
100
100
46.6
26.6
N.A.
20
20
N.A.
26.6
20
13.3
33.3
N.A.
13.3
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
8
0
0
8
8
16
0
0
8
8
8
8
% A
% Cys:
0
8
0
24
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
8
16
39
0
8
0
0
% D
% Glu:
0
0
0
0
8
8
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
8
8
0
16
24
8
0
0
0
8
% F
% Gly:
8
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
8
8
0
0
0
0
8
0
0
0
0
0
8
% H
% Ile:
8
8
8
0
0
16
16
0
0
0
0
0
16
16
8
% I
% Lys:
24
8
0
0
0
0
8
0
0
8
8
8
0
47
31
% K
% Leu:
0
16
24
8
0
8
0
0
8
0
8
8
8
8
16
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
16
16
16
8
24
16
0
0
0
% N
% Pro:
8
8
16
8
8
8
0
8
0
0
0
8
0
0
0
% P
% Gln:
0
8
0
0
16
24
8
0
0
0
0
8
0
0
0
% Q
% Arg:
0
8
8
8
16
0
8
16
0
8
0
0
16
0
0
% R
% Ser:
31
24
8
0
24
8
24
47
8
8
8
24
31
16
8
% S
% Thr:
8
0
16
39
16
0
0
8
8
24
8
0
16
8
0
% T
% Val:
0
0
0
0
0
8
8
0
8
8
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _