KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCRTR2
All Species:
13.64
Human Site:
T205
Identified Species:
25
UniProt:
O43614
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43614
NP_001517.2
444
50694
T205
P
G
L
A
N
K
T
T
L
F
T
V
C
D
E
Chimpanzee
Pan troglodytes
XP_518552
444
50692
T205
P
G
L
A
N
K
T
T
L
F
T
V
C
E
E
Rhesus Macaque
Macaca mulatta
Q9GK74
381
42711
D147
T
L
T
V
I
A
L
D
R
H
R
C
I
V
Y
Dog
Lupus familis
XP_544446
502
56267
L266
V
M
E
C
S
S
V
L
P
E
L
A
N
R
T
Cat
Felis silvestris
Mouse
Mus musculus
P58308
460
52443
T205
P
G
L
A
N
K
T
T
L
F
T
V
C
D
E
Rat
Rattus norvegicus
P56719
460
52471
T205
P
G
L
A
N
K
T
T
L
F
T
V
C
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507023
412
46359
V179
V
M
V
P
Q
A
V
V
M
E
R
S
T
I
L
Chicken
Gallus gallus
Q9DDN6
385
43491
R152
L
T
V
I
A
L
D
R
H
R
C
I
V
Y
H
Frog
Xenopus laevis
P70031
453
51139
V219
F
P
M
K
D
R
R
V
G
H
Q
C
R
L
V
Zebra Danio
Brachydanio rerio
NP_001073337
424
48183
M191
M
I
P
Q
A
V
V
M
E
S
S
S
L
M
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25931
464
53506
I224
T
K
R
Y
A
T
F
I
I
A
G
V
W
F
I
Honey Bee
Apis mellifera
XP_001120335
399
45437
P166
R
W
Y
A
I
C
F
P
L
R
F
K
S
T
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789606
462
52471
P206
H
T
P
S
I
N
K
P
V
W
L
S
K
C
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
28.3
58.7
N.A.
91
91
N.A.
66.8
26.7
21.6
67.7
N.A.
29
30.4
N.A.
34.4
Protein Similarity:
100
99.7
45
69.5
N.A.
93.2
93
N.A.
78.5
44.1
40.8
81.3
N.A.
46.1
46.6
N.A.
53.6
P-Site Identity:
100
93.3
0
0
N.A.
100
100
N.A.
0
0
0
0
N.A.
6.6
13.3
N.A.
0
P-Site Similarity:
100
100
0
6.6
N.A.
100
100
N.A.
13.3
13.3
20
6.6
N.A.
13.3
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
39
24
16
0
0
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
8
0
8
0
0
0
0
8
16
31
8
0
% C
% Asp:
0
0
0
0
8
0
8
8
0
0
0
0
0
24
0
% D
% Glu:
0
0
8
0
0
0
0
0
8
16
0
0
0
8
31
% E
% Phe:
8
0
0
0
0
0
16
0
0
31
8
0
0
8
0
% F
% Gly:
0
31
0
0
0
0
0
0
8
0
8
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
8
16
0
0
0
0
8
% H
% Ile:
0
8
0
8
24
0
0
8
8
0
0
8
8
8
8
% I
% Lys:
0
8
0
8
0
31
8
0
0
0
0
8
8
0
0
% K
% Leu:
8
8
31
0
0
8
8
8
39
0
16
0
8
8
8
% L
% Met:
8
16
8
0
0
0
0
8
8
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
31
8
0
0
0
0
0
0
8
0
0
% N
% Pro:
31
8
16
8
0
0
0
16
8
0
0
0
0
0
8
% P
% Gln:
0
0
0
8
8
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
8
0
8
0
0
8
8
8
8
16
16
0
8
8
0
% R
% Ser:
0
0
0
8
8
8
0
0
0
8
8
24
8
0
0
% S
% Thr:
16
16
8
0
0
8
31
31
0
0
31
0
8
8
16
% T
% Val:
16
0
16
8
0
8
24
16
8
0
0
39
8
8
8
% V
% Trp:
0
8
0
0
0
0
0
0
0
8
0
0
8
0
0
% W
% Tyr:
0
0
8
8
0
0
0
0
0
0
0
0
0
8
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _