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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCRTR2
All Species:
13.64
Human Site:
Y243
Identified Species:
25
UniProt:
O43614
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43614
NP_001517.2
444
50694
Y243
L
C
L
M
V
L
A
Y
L
Q
I
F
R
K
L
Chimpanzee
Pan troglodytes
XP_518552
444
50692
Y243
L
C
L
M
V
L
A
Y
L
Q
I
F
R
K
L
Rhesus Macaque
Macaca mulatta
Q9GK74
381
42711
I185
L
L
A
S
P
L
A
I
F
R
E
Y
S
L
I
Dog
Lupus familis
XP_544446
502
56267
P304
F
I
V
T
Y
L
A
P
L
G
L
M
A
M
A
Cat
Felis silvestris
Mouse
Mus musculus
P58308
460
52443
Y243
L
C
L
M
I
L
A
Y
L
Q
I
F
R
K
L
Rat
Rattus norvegicus
P56719
460
52471
Y243
L
C
L
M
V
L
A
Y
L
Q
I
F
R
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507023
412
46359
F217
K
I
Y
H
S
C
F
F
I
V
T
Y
L
A
P
Chicken
Gallus gallus
Q9DDN6
385
43491
F190
L
A
S
P
L
A
I
F
R
E
Y
S
L
I
E
Frog
Xenopus laevis
P70031
453
51139
G257
V
V
M
I
V
A
Y
G
L
I
S
R
E
L
Y
Zebra Danio
Brachydanio rerio
NP_001073337
424
48183
I229
V
Y
H
T
C
F
F
I
V
T
Y
F
A
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25931
464
53506
R262
K
C
E
K
Y
I
C
R
E
M
W
P
S
R
T
Honey Bee
Apis mellifera
XP_001120335
399
45437
K204
I
Y
C
F
S
L
N
K
Q
H
Y
E
K
N
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789606
462
52471
V244
L
P
L
C
V
I
T
V
A
Y
S
M
V
C
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
28.3
58.7
N.A.
91
91
N.A.
66.8
26.7
21.6
67.7
N.A.
29
30.4
N.A.
34.4
Protein Similarity:
100
99.7
45
69.5
N.A.
93.2
93
N.A.
78.5
44.1
40.8
81.3
N.A.
46.1
46.6
N.A.
53.6
P-Site Identity:
100
100
20
20
N.A.
93.3
100
N.A.
0
6.6
13.3
13.3
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
100
40
33.3
N.A.
100
100
N.A.
20
26.6
33.3
26.6
N.A.
20
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
16
47
0
8
0
0
0
16
8
8
% A
% Cys:
0
39
8
8
8
8
8
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
8
8
8
8
8
0
8
% E
% Phe:
8
0
0
8
0
8
16
16
8
0
0
39
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% G
% His:
0
0
8
8
0
0
0
0
0
8
0
0
0
0
8
% H
% Ile:
8
16
0
8
8
16
8
16
8
8
31
0
0
8
16
% I
% Lys:
16
0
0
8
0
0
0
8
0
0
0
0
8
31
0
% K
% Leu:
54
8
39
0
8
54
0
0
47
0
8
0
16
16
39
% L
% Met:
0
0
8
31
0
0
0
0
0
8
0
16
0
8
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
0
8
8
0
0
8
0
0
0
8
0
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
8
31
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
8
8
0
8
31
8
0
% R
% Ser:
0
0
8
8
16
0
0
0
0
0
16
8
16
0
0
% S
% Thr:
0
0
0
16
0
0
8
0
0
8
8
0
0
0
8
% T
% Val:
16
8
8
0
39
0
0
8
8
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
16
8
0
16
0
8
31
0
8
24
16
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _