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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCRTR2
All Species:
18.18
Human Site:
Y47
Identified Species:
33.33
UniProt:
O43614
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43614
NP_001517.2
444
50694
Y47
L
R
Y
L
W
R
E
Y
L
H
P
K
E
Y
E
Chimpanzee
Pan troglodytes
XP_518552
444
50692
Y47
L
R
Y
L
W
R
E
Y
L
H
P
K
E
Y
E
Rhesus Macaque
Macaca mulatta
Q9GK74
381
42711
Dog
Lupus familis
XP_544446
502
56267
Y116
L
R
Y
L
W
R
D
Y
L
Y
P
K
Q
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
P58308
460
52443
Y47
L
R
Y
L
W
R
E
Y
L
H
P
K
E
Y
E
Rat
Rattus norvegicus
P56719
460
52471
Y47
L
R
Y
L
W
R
E
Y
L
H
P
K
E
Y
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507023
412
46359
L32
D
D
E
F
L
R
Y
L
W
R
D
Y
L
Y
P
Chicken
Gallus gallus
Q9DDN6
385
43491
Frog
Xenopus laevis
P70031
453
51139
P61
P
I
L
D
R
K
K
P
S
P
S
D
L
N
L
Zebra Danio
Brachydanio rerio
NP_001073337
424
48183
W44
D
E
L
L
K
Y
I
W
R
E
Y
L
H
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25931
464
53506
D56
N
T
T
A
L
P
A
D
D
E
G
S
N
Y
G
Honey Bee
Apis mellifera
XP_001120335
399
45437
D19
I
D
A
T
D
S
D
D
Y
F
S
L
D
Y
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789606
462
52471
M48
F
Y
D
L
V
W
E
M
V
Y
P
Q
T
Y
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
28.3
58.7
N.A.
91
91
N.A.
66.8
26.7
21.6
67.7
N.A.
29
30.4
N.A.
34.4
Protein Similarity:
100
99.7
45
69.5
N.A.
93.2
93
N.A.
78.5
44.1
40.8
81.3
N.A.
46.1
46.6
N.A.
53.6
P-Site Identity:
100
100
0
80
N.A.
100
100
N.A.
13.3
0
0
6.6
N.A.
6.6
6.6
N.A.
33.3
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
13.3
0
13.3
20
N.A.
6.6
26.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
16
8
8
8
0
16
16
8
0
8
8
8
0
0
% D
% Glu:
0
8
8
0
0
0
39
0
0
16
0
0
31
0
47
% E
% Phe:
8
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
31
0
0
8
0
0
% H
% Ile:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
8
8
0
0
0
0
39
0
0
8
% K
% Leu:
39
0
16
54
16
0
0
8
39
0
0
16
16
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% N
% Pro:
8
0
0
0
0
8
0
8
0
8
47
0
0
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% Q
% Arg:
0
39
0
0
8
47
0
0
8
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
0
8
0
16
8
0
0
0
% S
% Thr:
0
8
8
8
0
0
0
0
0
0
0
0
8
0
8
% T
% Val:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
39
8
0
8
8
0
0
0
0
0
0
% W
% Tyr:
0
8
39
0
0
8
8
39
8
16
8
8
0
70
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _