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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TIMM44 All Species: 41.52
Human Site: S115 Identified Species: 65.24
UniProt: O43615 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43615 NP_006342.2 452 51356 S115 E S E T V R T S E V L R K K L
Chimpanzee Pan troglodytes XP_512338 699 77495 S362 E S E T V R T S E V L R K K L
Rhesus Macaque Macaca mulatta XP_001098363 442 50253 T116 R K K L G E L T G T V K E S L
Dog Lupus familis XP_542123 454 51492 S117 E S E T V R T S E V I K K K L
Cat Felis silvestris
Mouse Mus musculus O35857 452 51158 S115 E S E T V R T S E A I K K K L
Rat Rattus norvegicus O35094 453 51042 S116 E S E T V R T S E A I K K K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516222 452 50963 S117 E S E T V K T S E V I K K K F
Chicken Gallus gallus XP_418174 451 51246 S114 E S E T V K T S E V I K K K L
Frog Xenopus laevis NP_001087692 451 51552 S114 E L E T M K T S E V F K K K F
Zebra Danio Brachydanio rerio NP_001013525 452 50852 S116 E S E T V K T S E V L K K T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_732403 428 48907 V111 L G A I K E R V G D V L E D A
Honey Bee Apis mellifera XP_395866 456 52173 S122 E S E A T K G S E A L K E K L
Nematode Worm Caenorhab. elegans O02161 425 49380 E114 H M K K M V H E I Q K T E A G
Sea Urchin Strong. purpuratus XP_001203738 455 51737 K115 K K F E N L E K E T A K G S A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q01852 431 48836 T112 V G K T L K K T G E T M E H I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.3 95.5 92.5 N.A. 89.3 90 N.A. 76.5 82 73.8 75.6 N.A. 47.7 50.6 41.1 53.4
Protein Similarity: 100 64.3 97.1 97.3 N.A. 94.9 95.3 N.A. 87.1 92.9 86.9 86.5 N.A. 71 70.6 64.3 72.9
P-Site Identity: 100 100 6.6 86.6 N.A. 80 80 N.A. 73.3 80 60 80 N.A. 0 53.3 0 6.6
P-Site Similarity: 100 100 40 100 N.A. 93.3 93.3 N.A. 93.3 100 80 93.3 N.A. 13.3 73.3 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 0 0 0 0 0 20 7 0 0 7 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 7 0 0 0 7 0 % D
% Glu: 67 0 67 7 0 14 7 7 74 7 0 0 34 0 0 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 7 0 0 0 14 % F
% Gly: 0 14 0 0 7 0 7 0 20 0 0 0 7 0 7 % G
% His: 7 0 0 0 0 0 7 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 7 0 0 0 0 7 0 34 0 0 0 7 % I
% Lys: 7 14 20 7 7 40 7 7 0 0 7 67 60 60 0 % K
% Leu: 7 7 0 7 7 7 7 0 0 0 27 7 0 0 60 % L
% Met: 0 7 0 0 14 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 7 0 0 0 0 34 7 0 0 0 0 14 0 0 0 % R
% Ser: 0 60 0 0 0 0 0 67 0 0 0 0 0 14 0 % S
% Thr: 0 0 0 67 7 0 60 14 0 14 7 7 0 7 0 % T
% Val: 7 0 0 0 54 7 0 7 0 47 14 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _