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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIMM44
All Species:
36.36
Human Site:
S139
Identified Species:
57.14
UniProt:
O43615
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43615
NP_006342.2
452
51356
S139
S
L
H
E
V
S
K
S
D
L
G
R
K
I
K
Chimpanzee
Pan troglodytes
XP_512338
699
77495
S386
S
L
H
E
V
S
K
S
D
L
G
R
K
I
K
Rhesus Macaque
Macaca mulatta
XP_001098363
442
50253
E140
R
K
I
K
E
G
V
E
E
A
A
K
T
A
K
Dog
Lupus familis
XP_542123
454
51492
S141
S
L
D
E
V
S
K
S
D
L
G
R
K
I
K
Cat
Felis silvestris
Mouse
Mus musculus
O35857
452
51158
S139
S
L
D
E
V
S
K
S
D
L
G
R
K
I
K
Rat
Rattus norvegicus
O35094
453
51042
S140
S
L
D
E
V
S
K
S
D
L
G
R
K
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516222
452
50963
S141
S
L
D
E
V
S
K
S
D
I
G
R
K
I
K
Chicken
Gallus gallus
XP_418174
451
51246
S138
S
L
D
E
V
S
K
S
D
I
G
R
K
I
K
Frog
Xenopus laevis
NP_001087692
451
51552
S138
S
L
D
E
V
G
K
S
D
L
G
R
K
I
R
Zebra Danio
Brachydanio rerio
NP_001013525
452
50852
T140
G
L
E
E
V
G
R
T
D
I
G
K
K
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732403
428
48907
A135
T
E
E
L
S
K
K
A
R
G
V
S
D
T
I
Honey Bee
Apis mellifera
XP_395866
456
52173
T146
V
L
E
E
A
S
K
T
E
L
G
K
K
A
G
Nematode Worm
Caenorhab. elegans
O02161
425
49380
A138
A
L
K
Q
A
R
K
A
A
E
H
V
E
K
V
Sea Urchin
Strong. purpuratus
XP_001203738
455
51737
V139
K
D
K
V
S
K
G
V
E
E
A
Q
K
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q01852
431
48836
A136
G
K
N
T
R
K
A
A
A
A
T
A
K
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.3
95.5
92.5
N.A.
89.3
90
N.A.
76.5
82
73.8
75.6
N.A.
47.7
50.6
41.1
53.4
Protein Similarity:
100
64.3
97.1
97.3
N.A.
94.9
95.3
N.A.
87.1
92.9
86.9
86.5
N.A.
71
70.6
64.3
72.9
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
93.3
N.A.
86.6
86.6
80
53.3
N.A.
6.6
46.6
13.3
6.6
P-Site Similarity:
100
100
26.6
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
86.6
80
N.A.
20
66.6
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
14
0
7
20
14
14
14
7
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
40
0
0
0
0
0
60
0
0
0
7
0
0
% D
% Glu:
0
7
20
67
7
0
0
7
20
14
0
0
7
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
14
0
0
0
0
20
7
0
0
7
67
0
0
0
7
% G
% His:
0
0
14
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
20
0
0
0
60
7
% I
% Lys:
7
14
14
7
0
20
74
0
0
0
0
20
80
14
60
% K
% Leu:
0
74
0
7
0
0
0
0
0
47
0
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
0
7
0
7
0
% Q
% Arg:
7
0
0
0
7
7
7
0
7
0
0
54
0
0
7
% R
% Ser:
54
0
0
0
14
54
0
54
0
0
0
7
0
0
0
% S
% Thr:
7
0
0
7
0
0
0
14
0
0
7
0
7
7
0
% T
% Val:
7
0
0
7
60
0
7
7
0
0
7
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _