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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIMM44
All Species:
50
Human Site:
S276
Identified Species:
78.57
UniProt:
O43615
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43615
NP_006342.2
452
51356
S276
D
N
A
F
I
R
A
S
R
A
L
T
D
K
V
Chimpanzee
Pan troglodytes
XP_512338
699
77495
S523
D
N
A
F
I
R
A
S
R
A
L
T
D
K
V
Rhesus Macaque
Macaca mulatta
XP_001098363
442
50253
S266
D
N
A
F
I
R
A
S
R
A
L
T
D
K
V
Dog
Lupus familis
XP_542123
454
51492
S278
D
N
A
L
I
R
A
S
R
A
L
T
D
K
V
Cat
Felis silvestris
Mouse
Mus musculus
O35857
452
51158
S276
D
N
V
L
I
R
A
S
R
A
L
T
D
K
V
Rat
Rattus norvegicus
O35094
453
51042
S277
D
N
V
L
I
R
A
S
R
A
L
T
D
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516222
452
50963
S278
D
N
A
F
I
R
V
S
R
A
V
T
D
K
V
Chicken
Gallus gallus
XP_418174
451
51246
S275
D
N
A
F
I
R
A
S
R
A
V
T
D
K
V
Frog
Xenopus laevis
NP_001087692
451
51552
S275
D
N
A
F
V
R
A
S
R
T
I
T
D
K
V
Zebra Danio
Brachydanio rerio
NP_001013525
452
50852
S276
D
N
A
F
I
R
A
S
R
A
V
T
D
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732403
428
48907
S252
E
N
P
V
I
R
A
S
R
L
L
T
D
K
V
Honey Bee
Apis mellifera
XP_395866
456
52173
S280
D
N
P
V
I
R
A
S
R
L
L
T
E
K
V
Nematode Worm
Caenorhab. elegans
O02161
425
49380
V261
V
T
E
K
I
G
S
V
F
S
G
Q
N
E
V
Sea Urchin
Strong. purpuratus
XP_001203738
455
51737
S279
D
N
I
M
V
R
A
S
K
A
V
T
D
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q01852
431
48836
M254
E
N
P
L
I
V
V
M
R
K
I
T
N
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.3
95.5
92.5
N.A.
89.3
90
N.A.
76.5
82
73.8
75.6
N.A.
47.7
50.6
41.1
53.4
Protein Similarity:
100
64.3
97.1
97.3
N.A.
94.9
95.3
N.A.
87.1
92.9
86.9
86.5
N.A.
71
70.6
64.3
72.9
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
86.6
93.3
80
86.6
N.A.
73.3
73.3
13.3
60
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
93.3
100
93.3
100
N.A.
80
80
40
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
54
0
0
0
80
0
0
67
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
80
0
0
0
0
0
0
0
0
0
0
0
80
0
0
% D
% Glu:
14
0
7
0
0
0
0
0
0
0
0
0
7
7
0
% E
% Phe:
0
0
0
47
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
87
0
0
0
0
0
14
0
0
0
0
% I
% Lys:
0
0
0
7
0
0
0
0
7
7
0
0
0
87
0
% K
% Leu:
0
0
0
27
0
0
0
0
0
14
54
0
0
0
0
% L
% Met:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
7
% M
% Asn:
0
94
0
0
0
0
0
0
0
0
0
0
14
0
0
% N
% Pro:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
0
0
0
0
0
87
0
0
87
0
0
0
0
7
0
% R
% Ser:
0
0
0
0
0
0
7
87
0
7
0
0
0
0
0
% S
% Thr:
0
7
0
0
0
0
0
0
0
7
0
94
0
0
0
% T
% Val:
7
0
14
14
14
7
14
7
0
0
27
0
0
0
94
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _