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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIMM44
All Species:
33.33
Human Site:
Y104
Identified Species:
52.38
UniProt:
O43615
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43615
NP_006342.2
452
51356
Y104
L
Q
E
A
R
R
K
Y
K
T
I
E
S
E
T
Chimpanzee
Pan troglodytes
XP_512338
699
77495
Y351
L
Q
E
A
R
R
K
Y
K
T
I
E
S
E
T
Rhesus Macaque
Macaca mulatta
XP_001098363
442
50253
S105
E
S
E
T
M
R
T
S
E
V
L
R
K
K
L
Dog
Lupus familis
XP_542123
454
51492
Y106
L
Q
E
A
R
R
K
Y
K
T
I
E
S
E
T
Cat
Felis silvestris
Mouse
Mus musculus
O35857
452
51158
Y104
L
Q
E
A
R
R
K
Y
K
S
I
E
S
E
T
Rat
Rattus norvegicus
O35094
453
51042
Y105
L
Q
E
A
R
R
K
Y
K
T
I
E
S
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516222
452
50963
Y106
L
Q
E
A
R
R
K
Y
K
T
I
E
S
E
T
Chicken
Gallus gallus
XP_418174
451
51246
Y103
L
R
E
A
R
R
K
Y
K
T
I
E
S
E
T
Frog
Xenopus laevis
NP_001087692
451
51552
F103
L
Q
Q
A
R
R
K
F
K
T
I
E
L
E
T
Zebra Danio
Brachydanio rerio
NP_001013525
452
50852
Y105
L
K
Q
A
R
R
K
Y
K
T
I
E
S
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732403
428
48907
L100
A
Q
K
S
S
S
M
L
K
E
Q
L
G
A
I
Honey Bee
Apis mellifera
XP_395866
456
52173
F111
L
R
S
A
R
Q
K
F
Q
A
V
E
S
E
A
Nematode Worm
Caenorhab. elegans
O02161
425
49380
E103
V
V
K
Q
K
I
E
E
L
S
D
H
M
K
K
Sea Urchin
Strong. purpuratus
XP_001203738
455
51737
Q104
L
E
Q
S
D
A
L
Q
E
A
R
K
K
F
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q01852
431
48836
G101
A
Y
L
K
A
Q
R
G
S
T
I
V
G
K
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.3
95.5
92.5
N.A.
89.3
90
N.A.
76.5
82
73.8
75.6
N.A.
47.7
50.6
41.1
53.4
Protein Similarity:
100
64.3
97.1
97.3
N.A.
94.9
95.3
N.A.
87.1
92.9
86.9
86.5
N.A.
71
70.6
64.3
72.9
P-Site Identity:
100
100
13.3
100
N.A.
93.3
100
N.A.
100
93.3
80
86.6
N.A.
13.3
46.6
0
6.6
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
26.6
80
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
67
7
7
0
0
0
14
0
0
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
7
7
54
0
0
0
7
7
14
7
0
67
0
67
7
% E
% Phe:
0
0
0
0
0
0
0
14
0
0
0
0
0
7
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
0
0
14
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
0
0
67
0
0
0
7
% I
% Lys:
0
7
14
7
7
0
67
0
67
0
0
7
14
20
7
% K
% Leu:
74
0
7
0
0
0
7
7
7
0
7
7
7
0
7
% L
% Met:
0
0
0
0
7
0
7
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
54
20
7
0
14
0
7
7
0
7
0
0
0
0
% Q
% Arg:
0
14
0
0
67
67
7
0
0
0
7
7
0
0
0
% R
% Ser:
0
7
7
14
7
7
0
7
7
14
0
0
60
0
0
% S
% Thr:
0
0
0
7
0
0
7
0
0
60
0
0
0
0
67
% T
% Val:
7
7
0
0
0
0
0
0
0
7
7
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _