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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCK2
All Species:
16.67
Human Site:
S176
Identified Species:
33.33
UniProt:
O43639
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43639
NP_001004720.1
380
42915
S176
V
D
E
A
A
A
E
S
P
S
F
L
S
L
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109452
380
42927
S176
V
D
E
A
A
A
E
S
P
S
F
L
S
L
R
Dog
Lupus familis
XP_538440
380
42878
S176
M
D
E
A
A
A
E
S
P
R
F
L
S
L
R
Cat
Felis silvestris
Mouse
Mus musculus
NP_035009
380
42861
A176
A
D
E
A
A
A
E
A
P
S
F
L
S
L
R
Rat
Rattus norvegicus
NP_001101686
380
42891
A176
A
D
E
A
A
A
E
A
P
S
F
L
S
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506778
318
35630
V137
Q
S
L
K
I
L
H
V
V
Q
T
L
Y
P
F
Chicken
Gallus gallus
NP_001025985
380
43041
S176
V
E
E
A
T
A
D
S
P
S
F
L
S
L
R
Frog
Xenopus laevis
NP_001083313
381
43113
S177
V
D
D
E
T
A
D
S
P
S
F
L
N
S
R
Zebra Danio
Brachydanio rerio
NP_001003492
380
43022
L176
M
E
D
T
S
A
D
L
P
A
V
F
S
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722657
548
60388
N324
H
T
Y
A
M
A
E
N
V
L
D
I
V
V
A
Honey Bee
Apis mellifera
XP_624281
392
44184
H180
G
D
A
D
D
T
L
H
T
Y
A
M
A
E
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784072
389
44190
K178
H
G
S
S
T
S
S
K
G
D
D
N
S
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
97.6
N.A.
96
95.7
N.A.
75.5
92.8
82.6
81.5
N.A.
29.3
45.6
N.A.
45.5
Protein Similarity:
100
N.A.
99.7
98.9
N.A.
98.9
98.6
N.A.
81.5
98.1
93.4
90.7
N.A.
44.7
65.3
N.A.
63.5
P-Site Identity:
100
N.A.
100
86.6
N.A.
86.6
86.6
N.A.
6.6
80
60
20
N.A.
20
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
6.6
93.3
80
66.6
N.A.
40
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
59
42
75
0
17
0
9
9
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
59
17
9
9
0
25
0
0
9
17
0
0
0
0
% D
% Glu:
0
17
50
9
0
0
50
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
59
9
0
0
9
% F
% Gly:
9
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% G
% His:
17
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
9
0
9
0
% I
% Lys:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
0
9
9
9
0
9
0
67
0
50
0
% L
% Met:
17
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
9
9
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
67
0
0
0
0
9
9
% P
% Gln:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
59
% R
% Ser:
0
9
9
9
9
9
9
42
0
50
0
0
67
17
0
% S
% Thr:
0
9
0
9
25
9
0
0
9
0
9
0
0
0
0
% T
% Val:
34
0
0
0
0
0
0
9
17
0
9
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
9
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _