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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCK2
All Species:
26.06
Human Site:
S181
Identified Species:
52.12
UniProt:
O43639
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43639
NP_001004720.1
380
42915
S181
A
E
S
P
S
F
L
S
L
R
K
G
A
S
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109452
380
42927
S181
A
E
S
P
S
F
L
S
L
R
K
G
A
S
L
Dog
Lupus familis
XP_538440
380
42878
S181
A
E
S
P
R
F
L
S
L
R
K
G
A
S
L
Cat
Felis silvestris
Mouse
Mus musculus
NP_035009
380
42861
S181
A
E
A
P
S
F
L
S
L
R
R
G
T
A
L
Rat
Rattus norvegicus
NP_001101686
380
42891
S181
A
E
A
P
S
F
L
S
L
R
R
G
T
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506778
318
35630
Y142
L
H
V
V
Q
T
L
Y
P
F
S
S
V
T
E
Chicken
Gallus gallus
NP_001025985
380
43041
S181
A
D
S
P
S
F
L
S
L
R
K
G
A
S
M
Frog
Xenopus laevis
NP_001083313
381
43113
N182
A
D
S
P
S
F
L
N
S
R
K
G
A
S
M
Zebra Danio
Brachydanio rerio
NP_001003492
380
43022
S181
A
D
L
P
A
V
F
S
S
Q
P
G
L
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722657
548
60388
V329
A
E
N
V
L
D
I
V
V
A
L
Y
S
F
T
Honey Bee
Apis mellifera
XP_624281
392
44184
A185
T
L
H
T
Y
A
M
A
E
N
V
L
D
I
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784072
389
44190
S183
S
S
K
G
D
D
N
S
I
P
D
D
F
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
97.6
N.A.
96
95.7
N.A.
75.5
92.8
82.6
81.5
N.A.
29.3
45.6
N.A.
45.5
Protein Similarity:
100
N.A.
99.7
98.9
N.A.
98.9
98.6
N.A.
81.5
98.1
93.4
90.7
N.A.
44.7
65.3
N.A.
63.5
P-Site Identity:
100
N.A.
100
93.3
N.A.
73.3
73.3
N.A.
6.6
86.6
73.3
33.3
N.A.
13.3
0
N.A.
13.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
13.3
100
93.3
53.3
N.A.
40
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
75
0
17
0
9
9
0
9
0
9
0
0
42
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
25
0
0
9
17
0
0
0
0
9
9
9
0
0
% D
% Glu:
0
50
0
0
0
0
0
0
9
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
59
9
0
0
9
0
0
9
9
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
67
0
0
0
% G
% His:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
9
0
0
0
0
9
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
42
0
0
0
0
% K
% Leu:
9
9
9
0
9
0
67
0
50
0
9
9
9
0
50
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
17
% M
% Asn:
0
0
9
0
0
0
9
9
0
9
0
0
0
0
9
% N
% Pro:
0
0
0
67
0
0
0
0
9
9
9
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
59
17
0
0
0
0
% R
% Ser:
9
9
42
0
50
0
0
67
17
0
9
9
9
50
0
% S
% Thr:
9
0
0
9
0
9
0
0
0
0
0
0
17
9
9
% T
% Val:
0
0
9
17
0
9
0
9
9
0
9
0
9
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
9
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _