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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCK2
All Species:
11.21
Human Site:
S276
Identified Species:
22.42
UniProt:
O43639
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43639
NP_001004720.1
380
42915
S276
I
S
Y
T
G
P
S
S
S
G
R
F
A
G
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109452
380
42927
S276
I
S
Y
T
G
P
S
S
S
G
R
F
A
G
R
Dog
Lupus familis
XP_538440
380
42878
C276
I
S
Y
A
G
P
A
C
S
G
R
F
A
G
R
Cat
Felis silvestris
Mouse
Mus musculus
NP_035009
380
42861
A276
I
S
Y
T
G
P
S
A
S
G
R
F
A
G
R
Rat
Rattus norvegicus
NP_001101686
380
42891
A276
I
S
Y
T
G
P
S
A
S
G
R
F
A
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506778
318
35630
E222
T
G
R
F
A
G
R
E
W
Y
Y
G
N
V
T
Chicken
Gallus gallus
NP_001025985
380
43041
S276
I
S
Y
T
G
P
S
S
T
G
R
F
A
G
R
Frog
Xenopus laevis
NP_001083313
381
43113
C277
I
S
Y
T
G
P
A
C
T
G
R
F
A
G
K
Zebra Danio
Brachydanio rerio
NP_001003492
380
43022
H276
N
S
H
T
G
P
S
H
T
G
L
F
A
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722657
548
60388
E439
Q
S
S
G
Q
P
I
E
R
P
N
L
A
G
K
Honey Bee
Apis mellifera
XP_624281
392
44184
G268
T
S
S
E
I
S
T
G
D
S
L
E
R
R
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784072
389
44190
S282
D
N
S
F
T
P
S
S
S
V
G
F
Y
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
97.6
N.A.
96
95.7
N.A.
75.5
92.8
82.6
81.5
N.A.
29.3
45.6
N.A.
45.5
Protein Similarity:
100
N.A.
99.7
98.9
N.A.
98.9
98.6
N.A.
81.5
98.1
93.4
90.7
N.A.
44.7
65.3
N.A.
63.5
P-Site Identity:
100
N.A.
100
80
N.A.
93.3
93.3
N.A.
0
93.3
73.3
60
N.A.
26.6
6.6
N.A.
40
P-Site Similarity:
100
N.A.
100
86.6
N.A.
100
100
N.A.
0
100
93.3
80
N.A.
33.3
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
17
17
0
0
0
0
75
0
0
% A
% Cys:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% D
% Glu:
0
0
0
9
0
0
0
17
0
0
0
9
0
0
0
% E
% Phe:
0
0
0
17
0
0
0
0
0
0
0
75
0
0
0
% F
% Gly:
0
9
0
9
67
9
0
9
0
67
9
9
0
75
0
% G
% His:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
59
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
17
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
0
0
0
0
0
0
0
0
9
0
9
0
0
% N
% Pro:
0
0
0
0
0
84
0
0
0
9
0
0
0
0
9
% P
% Gln:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
0
9
0
9
0
59
0
9
9
59
% R
% Ser:
0
84
25
0
0
9
59
34
50
9
0
0
0
0
0
% S
% Thr:
17
0
0
59
9
0
9
0
25
0
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
59
0
0
0
0
0
0
9
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _