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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSPAN6
All Species:
7.88
Human Site:
S135
Identified Species:
17.33
UniProt:
O43657
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43657
NP_003261.1
245
27563
S135
K
A
L
K
Q
Y
N
S
T
G
D
Y
R
S
H
Chimpanzee
Pan troglodytes
Q7YQL0
244
26954
N127
T
D
A
M
Q
T
Y
N
G
N
D
E
R
S
R
Rhesus Macaque
Macaca mulatta
XP_001091467
286
31632
A180
A
W
M
L
K
L
Y
A
M
F
L
T
L
I
F
Dog
Lupus familis
XP_538102
245
27638
S135
R
T
L
K
Q
Y
N
S
T
G
D
Y
R
S
D
Cat
Felis silvestris
Mouse
Mus musculus
O70401
245
27314
S135
N
A
L
K
E
Y
N
S
T
G
D
Y
R
S
E
Rat
Rattus norvegicus
P28648
238
25680
L127
Q
K
Q
M
Q
N
Y
L
T
D
N
K
T
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513327
239
26532
N128
T
E
A
M
Q
N
Y
N
G
N
D
E
R
S
R
Chicken
Gallus gallus
XP_420247
252
27809
G135
L
A
L
K
N
Y
N
G
T
A
D
H
H
S
E
Frog
Xenopus laevis
Q6DCQ3
239
26764
E129
G
L
L
L
Y
N
S
E
N
N
V
G
L
K
N
Zebra Danio
Brachydanio rerio
Q5RH71
281
31706
D137
N
A
I
K
H
Y
R
D
D
L
D
L
Q
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395922
241
26478
G131
N
E
T
M
S
V
Y
G
L
D
E
R
K
S
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.3
31.4
94.6
N.A.
92.6
27.3
N.A.
49.3
66.2
28.5
25.6
N.A.
N.A.
32.2
N.A.
N.A.
Protein Similarity:
100
74.6
45
98.3
N.A.
94.6
52.2
N.A.
66.1
79.7
47.3
48
N.A.
N.A.
55
N.A.
N.A.
P-Site Identity:
100
26.6
0
80
N.A.
80
13.3
N.A.
26.6
53.3
6.6
26.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
33.3
20
86.6
N.A.
86.6
33.3
N.A.
33.3
60
20
46.6
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
37
19
0
0
0
0
10
0
10
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
10
10
19
64
0
0
0
10
% D
% Glu:
0
19
0
0
10
0
0
10
0
0
10
19
0
0
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% F
% Gly:
10
0
0
0
0
0
0
19
19
28
0
10
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
10
10
0
10
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
10
10
0
46
10
0
0
0
0
0
0
10
10
10
0
% K
% Leu:
10
10
46
19
0
10
0
10
10
10
10
10
19
0
10
% L
% Met:
0
0
10
37
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
28
0
0
0
10
28
37
19
10
28
10
0
0
10
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
10
0
46
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
10
0
0
0
0
0
10
0
0
0
0
10
46
0
19
% R
% Ser:
0
0
0
0
10
0
10
28
0
0
0
0
0
64
0
% S
% Thr:
19
10
10
0
0
10
0
0
46
0
0
10
10
0
10
% T
% Val:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
46
46
0
0
0
0
28
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _