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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLRG1 All Species: 27.88
Human Site: S121 Identified Species: 40.89
UniProt: O43660 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43660 NP_002660.1 514 57194 S121 I Q R M P S E S A A Q S L A V
Chimpanzee Pan troglodytes Q5IS43 410 46712 E25 Y L R S N G Y E E A Y S V F K
Rhesus Macaque Macaca mulatta XP_001089346 547 60466 S121 I Q R M P S E S A A Q S L A V
Dog Lupus familis XP_855313 547 60496 S153 I Q R M P S E S A A Q S L A V
Cat Felis silvestris
Mouse Mus musculus Q922V4 513 56919 S121 I Q R M P S E S A A Q S L A V
Rat Rattus norvegicus Q9WUC8 514 57170 S121 I Q R M P S E S A A Q S L A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512213 555 61022 S160 I Q R M P S E S A A Q S L A V
Chicken Gallus gallus XP_420368 516 57103 S121 I Q R I P S E S A T Q S L A V
Frog Xenopus laevis NP_001088527 517 57610 A124 R M P S E S A A Q S L A L A L
Zebra Danio Brachydanio rerio NP_998605 511 56829 V121 K M P S E M G V H S M A L A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3J8 361 39023
Honey Bee Apis mellifera XP_624578 463 51840 T79 V Q N E N E N T D P P P P G D
Nematode Worm Caenorhab. elegans Q93794 587 65293 V150 D L L K V A Q V S K N W K L I
Sea Urchin Strong. purpuratus XP_799009 514 56726 V121 P G L S Q G G V Q Q V L R G L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42384 486 53991 E102 S T Q K G A T E S A I V V G P
Baker's Yeast Sacchar. cerevisiae Q12417 451 50682 K67 S F S G E G K K V T L Q H V P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20.6 91.2 90.1 N.A. 96.1 96.3 N.A. 84.1 88.1 85.3 77.8 N.A. 20.4 61.2 22.1 63.2
Protein Similarity: 100 37.3 92.1 91 N.A. 97.4 97.8 N.A. 87.5 92.6 90.9 86.7 N.A. 34.8 72.9 40.3 76.8
P-Site Identity: 100 20 100 100 N.A. 100 100 N.A. 100 86.6 20 13.3 N.A. 0 6.6 0 0
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 100 93.3 46.6 33.3 N.A. 0 20 26.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. 46.8 38.9 N.A.
Protein Similarity: N.A. N.A. N.A. 63.8 57.9 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 13 7 7 44 50 0 13 0 57 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 7 0 0 0 0 0 7 % D
% Glu: 0 0 0 7 19 7 44 13 7 0 0 0 0 0 0 % E
% Phe: 0 7 0 0 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 0 7 0 7 7 19 13 0 0 0 0 0 0 19 0 % G
% His: 0 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % H
% Ile: 44 0 0 7 0 0 0 0 0 0 7 0 0 0 7 % I
% Lys: 7 0 0 13 0 0 7 7 0 7 0 0 7 0 7 % K
% Leu: 0 13 13 0 0 0 0 0 0 0 13 7 57 7 19 % L
% Met: 0 13 0 38 0 7 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 7 0 13 0 7 0 0 0 7 0 0 0 0 % N
% Pro: 7 0 13 0 44 0 0 0 0 7 7 7 7 0 13 % P
% Gln: 0 50 7 0 7 0 7 0 13 7 44 7 0 0 0 % Q
% Arg: 7 0 50 0 0 0 0 0 0 0 0 0 7 0 0 % R
% Ser: 13 0 7 25 0 50 0 44 13 13 0 50 0 0 0 % S
% Thr: 0 7 0 0 0 0 7 7 0 13 0 0 0 0 0 % T
% Val: 7 0 0 0 7 0 0 19 7 0 7 7 13 7 44 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 7 0 0 0 0 0 7 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _