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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLRG1
All Species:
14.85
Human Site:
S154
Identified Species:
21.78
UniProt:
O43660
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43660
NP_002660.1
514
57194
S154
E
Y
R
H
P
G
A
S
D
R
P
Q
P
T
A
Chimpanzee
Pan troglodytes
Q5IS43
410
46712
V58
L
E
K
K
W
T
S
V
I
R
L
Q
K
K
V
Rhesus Macaque
Macaca mulatta
XP_001089346
547
60466
S154
E
Y
R
H
P
G
A
S
D
R
P
Q
P
T
A
Dog
Lupus familis
XP_855313
547
60496
T186
G
E
Y
R
H
P
G
T
S
D
R
S
Q
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q922V4
513
56919
S154
E
Y
R
H
P
G
A
S
D
R
S
Q
P
T
A
Rat
Rattus norvegicus
Q9WUC8
514
57170
S154
E
Y
R
H
P
G
A
S
D
R
S
Q
P
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512213
555
61022
G193
G
D
I
Y
R
H
A
G
I
A
E
R
S
Q
P
Chicken
Gallus gallus
XP_420368
516
57103
G154
G
E
I
Y
R
H
A
G
I
S
E
R
S
Q
P
Frog
Xenopus laevis
NP_001088527
517
57610
A157
I
Y
R
H
A
G
L
A
E
R
S
Q
P
P
G
Zebra Danio
Brachydanio rerio
NP_998605
511
56829
A154
I
H
R
H
A
G
G
A
E
R
S
H
P
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
G9
V
P
I
G
A
V
H
G
G
H
P
G
V
V
H
Honey Bee
Apis mellifera
XP_624578
463
51840
Q112
N
N
N
I
V
T
T
Q
T
N
S
G
G
N
A
Nematode Worm
Caenorhab. elegans
Q93794
587
65293
T183
P
D
P
T
D
R
V
T
G
A
W
Q
G
T
A
Sea Urchin
Strong. purpuratus
XP_799009
514
56726
P154
I
Q
R
K
A
G
I
P
E
R
I
Q
P
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42384
486
53991
A135
K
S
T
T
I
I
P
A
N
V
S
S
Y
Q
R
Baker's Yeast
Sacchar. cerevisiae
Q12417
451
50682
K100
H
A
S
A
F
V
N
K
I
F
Q
P
E
V
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.6
91.2
90.1
N.A.
96.1
96.3
N.A.
84.1
88.1
85.3
77.8
N.A.
20.4
61.2
22.1
63.2
Protein Similarity:
100
37.3
92.1
91
N.A.
97.4
97.8
N.A.
87.5
92.6
90.9
86.7
N.A.
34.8
72.9
40.3
76.8
P-Site Identity:
100
13.3
100
6.6
N.A.
93.3
93.3
N.A.
6.6
6.6
46.6
33.3
N.A.
6.6
6.6
20
33.3
P-Site Similarity:
100
26.6
100
13.3
N.A.
93.3
93.3
N.A.
20
20
60
53.3
N.A.
6.6
6.6
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.8
38.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.8
57.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
25
0
38
19
0
13
0
0
0
0
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
7
0
0
0
25
7
0
0
0
0
0
% D
% Glu:
25
19
0
0
0
0
0
0
19
0
13
0
7
0
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
19
0
0
7
0
44
13
19
13
0
0
13
13
0
13
% G
% His:
7
7
0
38
7
13
7
0
0
7
0
7
0
0
7
% H
% Ile:
19
0
19
7
7
7
7
0
25
0
7
0
0
0
0
% I
% Lys:
7
0
7
13
0
0
0
7
0
0
0
0
7
7
0
% K
% Leu:
7
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
7
0
0
0
7
0
7
7
0
0
0
7
0
% N
% Pro:
7
7
7
0
25
7
7
7
0
0
19
7
44
25
13
% P
% Gln:
0
7
0
0
0
0
0
7
0
0
7
50
7
19
7
% Q
% Arg:
0
0
44
7
13
7
0
0
0
50
7
13
0
0
7
% R
% Ser:
0
7
7
0
0
0
7
25
7
7
38
13
13
0
0
% S
% Thr:
0
0
7
13
0
13
7
13
7
0
0
0
0
32
0
% T
% Val:
7
0
0
0
7
13
7
7
0
7
0
0
7
13
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
32
7
13
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _