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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLRG1
All Species:
40.91
Human Site:
S374
Identified Species:
60
UniProt:
O43660
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43660
NP_002660.1
514
57194
S374
T
L
T
N
H
K
K
S
V
R
A
V
V
L
H
Chimpanzee
Pan troglodytes
Q5IS43
410
46712
R273
K
E
C
K
A
E
L
R
E
H
E
H
V
V
E
Rhesus Macaque
Macaca mulatta
XP_001089346
547
60466
S374
T
L
T
N
H
K
K
S
V
R
A
V
V
L
H
Dog
Lupus familis
XP_855313
547
60496
S407
T
L
T
N
H
K
K
S
V
R
A
V
V
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q922V4
513
56919
S373
T
L
T
N
H
K
K
S
V
R
A
V
V
L
H
Rat
Rattus norvegicus
Q9WUC8
514
57170
S374
T
L
T
N
H
K
K
S
V
R
A
V
V
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512213
555
61022
S415
T
L
T
N
H
K
K
S
V
R
A
V
V
L
H
Chicken
Gallus gallus
XP_420368
516
57103
S376
T
L
T
N
H
K
K
S
V
R
A
V
I
L
H
Frog
Xenopus laevis
NP_001088527
517
57610
S377
T
L
T
N
H
K
K
S
V
R
A
V
V
L
H
Zebra Danio
Brachydanio rerio
NP_998605
511
56829
S371
T
L
T
N
H
K
K
S
V
R
A
L
V
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
W225
Y
D
G
L
C
R
I
W
D
T
A
S
G
Q
C
Honey Bee
Apis mellifera
XP_624578
463
51840
V327
H
K
K
S
V
R
A
V
T
F
H
P
S
L
Y
Nematode Worm
Caenorhab. elegans
Q93794
587
65293
R420
T
L
T
G
H
N
N
R
V
Y
S
L
L
F
E
Sea Urchin
Strong. purpuratus
XP_799009
514
56726
S374
T
L
T
N
H
K
K
S
V
R
S
V
V
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42384
486
53991
M350
H
K
K
S
V
R
A
M
T
L
H
P
K
E
N
Baker's Yeast
Sacchar. cerevisiae
Q12417
451
50682
A315
K
R
S
V
R
A
T
A
L
H
P
K
E
F
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.6
91.2
90.1
N.A.
96.1
96.3
N.A.
84.1
88.1
85.3
77.8
N.A.
20.4
61.2
22.1
63.2
Protein Similarity:
100
37.3
92.1
91
N.A.
97.4
97.8
N.A.
87.5
92.6
90.9
86.7
N.A.
34.8
72.9
40.3
76.8
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
100
93.3
100
93.3
N.A.
6.6
6.6
33.3
93.3
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
13.3
26.6
53.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.8
38.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.8
57.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
13
7
0
0
63
0
0
0
0
% A
% Cys:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
0
7
0
0
0
7
0
0
7
0
7
0
7
7
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
13
0
% F
% Gly:
0
0
7
7
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
13
0
0
0
69
0
0
0
0
13
13
7
0
0
63
% H
% Ile:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% I
% Lys:
13
13
13
7
0
63
63
0
0
0
0
7
7
0
0
% K
% Leu:
0
69
0
7
0
0
7
0
7
7
0
13
7
69
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
63
0
7
7
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
7
13
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
7
0
0
7
19
0
13
0
63
0
0
0
0
0
% R
% Ser:
0
0
7
13
0
0
0
63
0
0
13
7
7
0
7
% S
% Thr:
69
0
69
0
0
0
7
0
13
7
0
0
0
0
0
% T
% Val:
0
0
0
7
13
0
0
7
69
0
0
57
63
7
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _