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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLRG1 All Species: 41.21
Human Site: S429 Identified Species: 60.44
UniProt: O43660 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43660 NP_002660.1 514 57194 S429 N S D G V L V S G A D N G T M
Chimpanzee Pan troglodytes Q5IS43 410 46712 G328 K M W D V S T G M C L M T L V
Rhesus Macaque Macaca mulatta XP_001089346 547 60466 S429 N S D G V L V S G A D N G T M
Dog Lupus familis XP_855313 547 60496 S462 N S D G V L V S G A D N G T M
Cat Felis silvestris
Mouse Mus musculus Q922V4 513 56919 S428 N A D G V L V S G A D N G T M
Rat Rattus norvegicus Q9WUC8 514 57170 S429 N T D G V L V S G A D N G T M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512213 555 61022 S470 N S D G V L V S G A D N G T M
Chicken Gallus gallus XP_420368 516 57103 S431 N S D G V L V S G A D N G T M
Frog Xenopus laevis NP_001088527 517 57610 S432 N S D G V L V S G A D N G T M
Zebra Danio Brachydanio rerio NP_998605 511 56829 S426 N S D G V L V S G A D N G T I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3J8 361 39023 T280 G K C L K T Y T G H K N E K Y
Honey Bee Apis mellifera XP_624578 463 51840 N382 V L V S G A D N G T M H L W D
Nematode Worm Caenorhab. elegans Q93794 587 65293 I475 G M Q L R G N I L V S C N A D
Sea Urchin Strong. purpuratus XP_799009 514 56726 S429 N S D N V L V S G G D N G S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42384 486 53991 D405 G V M V T G G D N G S I W F W
Baker's Yeast Sacchar. cerevisiae Q12417 451 50682 N370 V L F A G G D N G V L S F Y D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20.6 91.2 90.1 N.A. 96.1 96.3 N.A. 84.1 88.1 85.3 77.8 N.A. 20.4 61.2 22.1 63.2
Protein Similarity: 100 37.3 92.1 91 N.A. 97.4 97.8 N.A. 87.5 92.6 90.9 86.7 N.A. 34.8 72.9 40.3 76.8
P-Site Identity: 100 6.6 100 100 N.A. 93.3 93.3 N.A. 100 100 100 93.3 N.A. 13.3 6.6 0 73.3
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 20 20 0 86.6
Percent
Protein Identity: N.A. N.A. N.A. 46.8 38.9 N.A.
Protein Similarity: N.A. N.A. N.A. 63.8 57.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 0 7 0 0 0 57 0 0 0 7 0 % A
% Cys: 0 0 7 0 0 0 0 0 0 7 0 7 0 0 0 % C
% Asp: 0 0 63 7 0 0 13 7 0 0 63 0 0 0 19 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 0 0 7 7 0 % F
% Gly: 19 0 0 57 13 19 7 7 82 13 0 0 63 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 7 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 7 % I
% Lys: 7 7 0 0 7 0 0 0 0 0 7 0 0 7 0 % K
% Leu: 0 13 0 13 0 63 0 0 7 0 13 0 7 7 7 % L
% Met: 0 13 7 0 0 0 0 0 7 0 7 7 0 0 50 % M
% Asn: 63 0 0 7 0 0 7 13 7 0 0 69 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 50 0 7 0 7 0 63 0 0 13 7 0 7 0 % S
% Thr: 0 7 0 0 7 7 7 7 0 7 0 0 7 57 0 % T
% Val: 13 7 7 7 69 0 63 0 0 13 0 0 0 0 7 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 7 7 7 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _