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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLRG1 All Species: 14.24
Human Site: S61 Identified Species: 20.89
UniProt: O43660 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43660 NP_002660.1 514 57194 S61 P V L H M P T S K E N L K E K
Chimpanzee Pan troglodytes Q5IS43 410 46712
Rhesus Macaque Macaca mulatta XP_001089346 547 60466 L61 P V L H M P T L K E N L K E K
Dog Lupus familis XP_855313 547 60496 S93 P V L H M P T S K E N F K E K
Cat Felis silvestris
Mouse Mus musculus Q922V4 513 56919 S61 P V L H M P T S K E N L K E K
Rat Rattus norvegicus Q9WUC8 514 57170 S61 P V L H M P T S K E N L K E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512213 555 61022 V100 P V L H M P I V K E N F R E K
Chicken Gallus gallus XP_420368 516 57103 L61 S V L H M P T L K E N M R E K
Frog Xenopus laevis NP_001088527 517 57610 H64 T E Y S S V M H M P I L K E N
Zebra Danio Brachydanio rerio NP_998605 511 56829 L61 A V L H M P V L K E G R E K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3J8 361 39023
Honey Bee Apis mellifera XP_624578 463 51840 V19 R H S V H T L V F R S L K R T
Nematode Worm Caenorhab. elegans Q93794 587 65293 A90 L F K D L S S A E Q M D A F T
Sea Urchin Strong. purpuratus XP_799009 514 56726 T61 V Q N L T A T T G H Q R I A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42384 486 53991 D42 H G Q F P P P D P E A K Q I R
Baker's Yeast Sacchar. cerevisiae Q12417 451 50682
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20.6 91.2 90.1 N.A. 96.1 96.3 N.A. 84.1 88.1 85.3 77.8 N.A. 20.4 61.2 22.1 63.2
Protein Similarity: 100 37.3 92.1 91 N.A. 97.4 97.8 N.A. 87.5 92.6 90.9 86.7 N.A. 34.8 72.9 40.3 76.8
P-Site Identity: 100 0 93.3 93.3 N.A. 100 100 N.A. 73.3 73.3 20 46.6 N.A. 0 13.3 0 6.6
P-Site Similarity: 100 0 93.3 93.3 N.A. 100 100 N.A. 80 86.6 20 60 N.A. 0 20 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. 46.8 38.9 N.A.
Protein Similarity: N.A. N.A. N.A. 63.8 57.9 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 7 0 7 0 0 7 0 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 0 0 7 0 0 0 7 0 0 0 % D
% Glu: 0 7 0 0 0 0 0 0 7 57 0 0 7 50 7 % E
% Phe: 0 7 0 7 0 0 0 0 7 0 0 13 0 7 0 % F
% Gly: 0 7 0 0 0 0 0 0 7 0 7 0 0 0 7 % G
% His: 7 7 0 50 7 0 0 7 0 7 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 7 0 0 0 7 0 7 7 0 % I
% Lys: 0 0 7 0 0 0 0 0 50 0 0 7 44 7 44 % K
% Leu: 7 0 50 7 7 0 7 19 0 0 0 38 0 0 0 % L
% Met: 0 0 0 0 50 0 7 0 7 0 7 7 0 0 0 % M
% Asn: 0 0 7 0 0 0 0 0 0 0 44 0 0 0 7 % N
% Pro: 38 0 0 0 7 57 7 0 7 7 0 0 0 0 0 % P
% Gln: 0 7 7 0 0 0 0 0 0 7 7 0 7 0 0 % Q
% Arg: 7 0 0 0 0 0 0 0 0 7 0 13 13 7 7 % R
% Ser: 7 0 7 7 7 7 7 25 0 0 7 0 0 0 0 % S
% Thr: 7 0 0 0 7 7 44 7 0 0 0 0 0 0 13 % T
% Val: 7 50 0 7 0 7 7 13 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _