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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLRG1
All Species:
40
Human Site:
Y260
Identified Species:
58.67
UniProt:
O43660
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43660
NP_002660.1
514
57194
Y260
I
V
S
T
R
S
P
Y
L
F
S
C
G
E
D
Chimpanzee
Pan troglodytes
Q5IS43
410
46712
D159
S
V
Q
D
I
S
F
D
H
S
G
K
L
L
A
Rhesus Macaque
Macaca mulatta
XP_001089346
547
60466
Y260
I
V
S
T
R
S
P
Y
L
F
S
C
G
E
D
Dog
Lupus familis
XP_855313
547
60496
Y293
I
V
S
T
R
S
P
Y
L
F
S
C
G
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q922V4
513
56919
Y259
I
V
S
T
R
S
P
Y
L
F
S
C
G
E
D
Rat
Rattus norvegicus
Q9WUC8
514
57170
Y260
I
V
S
T
R
S
P
Y
L
F
S
C
G
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512213
555
61022
Y301
I
V
S
G
R
S
P
Y
L
F
S
C
G
E
D
Chicken
Gallus gallus
XP_420368
516
57103
Y262
I
V
S
A
R
S
P
Y
L
F
S
C
G
E
D
Frog
Xenopus laevis
NP_001088527
517
57610
Y263
I
V
S
G
R
S
P
Y
L
F
S
C
G
E
D
Zebra Danio
Brachydanio rerio
NP_998605
511
56829
Y257
A
V
S
N
R
S
P
Y
L
F
S
C
G
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
S111
G
K
F
E
K
T
I
S
G
H
K
L
G
I
S
Honey Bee
Apis mellifera
XP_624578
463
51840
C213
R
H
P
Y
L
F
S
C
G
E
D
R
Q
V
K
Nematode Worm
Caenorhab. elegans
Q93794
587
65293
Q306
V
W
T
S
Q
I
S
Q
C
G
R
Y
I
V
S
Sea Urchin
Strong. purpuratus
XP_799009
514
56726
Y260
A
V
S
P
R
Q
P
Y
L
F
S
C
G
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42384
486
53991
A236
R
H
T
Y
M
F
S
A
G
D
D
K
Q
V
K
Baker's Yeast
Sacchar. cerevisiae
Q12417
451
50682
S201
H
P
Y
L
F
S
V
S
E
D
K
T
V
K
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.6
91.2
90.1
N.A.
96.1
96.3
N.A.
84.1
88.1
85.3
77.8
N.A.
20.4
61.2
22.1
63.2
Protein Similarity:
100
37.3
92.1
91
N.A.
97.4
97.8
N.A.
87.5
92.6
90.9
86.7
N.A.
34.8
72.9
40.3
76.8
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
86.6
N.A.
6.6
0
0
80
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
86.6
N.A.
20
0
26.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.8
38.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.8
57.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
7
0
0
0
7
0
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
7
7
0
0
63
0
0
7
% C
% Asp:
0
0
0
7
0
0
0
7
0
13
13
0
0
0
63
% D
% Glu:
0
0
0
7
0
0
0
0
7
7
0
0
0
63
0
% E
% Phe:
0
0
7
0
7
13
7
0
0
63
0
0
0
0
0
% F
% Gly:
7
0
0
13
0
0
0
0
19
7
7
0
69
0
0
% G
% His:
7
13
0
0
0
0
0
0
7
7
0
0
0
0
0
% H
% Ile:
50
0
0
0
7
7
7
0
0
0
0
0
7
7
0
% I
% Lys:
0
7
0
0
7
0
0
0
0
0
13
13
0
7
13
% K
% Leu:
0
0
0
7
7
0
0
0
63
0
0
7
7
7
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
7
7
7
0
0
63
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
7
7
0
7
0
0
0
0
13
0
0
% Q
% Arg:
13
0
0
0
63
0
0
0
0
0
7
7
0
0
0
% R
% Ser:
7
0
63
7
0
69
19
13
0
7
63
0
0
0
13
% S
% Thr:
0
0
13
32
0
7
0
0
0
0
0
7
0
0
0
% T
% Val:
7
69
0
0
0
0
7
0
0
0
0
0
7
19
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
13
0
0
0
63
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _