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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLRG1 All Species: 24.24
Human Site: Y77 Identified Species: 35.56
UniProt: O43660 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43660 NP_002660.1 514 57194 Y77 P Q N A T D S Y V H K Q Y P A
Chimpanzee Pan troglodytes Q5IS43 410 46712
Rhesus Macaque Macaca mulatta XP_001089346 547 60466 Y77 P Q N A T D S Y V H K Q Y P A
Dog Lupus familis XP_855313 547 60496 Y109 P Q N A S D S Y G H K Q Y P A
Cat Felis silvestris
Mouse Mus musculus Q922V4 513 56919 Y77 P Q N A T D S Y P H K Q Y P A
Rat Rattus norvegicus Q9WUC8 514 57170 Y77 P Q N A P D S Y P H K Q Y P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512213 555 61022 Y116 P Q S S V D A Y G H K Q Y P A
Chicken Gallus gallus XP_420368 516 57103 Y77 G P A T G D P Y G H K Q Y S G
Frog Xenopus laevis NP_001088527 517 57610 H80 E K G H H E A H E H Y T A H Q
Zebra Danio Brachydanio rerio NP_998605 511 56829 G77 L H T S D P Y G Q S A Y P L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3J8 361 39023
Honey Bee Apis mellifera XP_624578 463 51840 G35 D M F L L N Q G T L P P M D P
Nematode Worm Caenorhab. elegans Q93794 587 65293 T106 L L Q E S N M T N I R Q L R A
Sea Urchin Strong. purpuratus XP_799009 514 56726 E77 S H Q G T R E E S Q G Y E Q G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42384 486 53991 F58 S H K M K V A F G G V E P V V
Baker's Yeast Sacchar. cerevisiae Q12417 451 50682 W23 K F Y S R I R W N N Q F S Y M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20.6 91.2 90.1 N.A. 96.1 96.3 N.A. 84.1 88.1 85.3 77.8 N.A. 20.4 61.2 22.1 63.2
Protein Similarity: 100 37.3 92.1 91 N.A. 97.4 97.8 N.A. 87.5 92.6 90.9 86.7 N.A. 34.8 72.9 40.3 76.8
P-Site Identity: 100 0 100 86.6 N.A. 93.3 86.6 N.A. 66.6 40 6.6 0 N.A. 0 0 13.3 6.6
P-Site Similarity: 100 0 100 93.3 N.A. 93.3 86.6 N.A. 86.6 40 33.3 6.6 N.A. 0 6.6 33.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. 46.8 38.9 N.A.
Protein Similarity: N.A. N.A. N.A. 63.8 57.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 32 0 0 19 0 0 0 7 0 7 0 44 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 7 44 0 0 0 0 0 0 0 7 0 % D
% Glu: 7 0 0 7 0 7 7 7 7 0 0 7 7 0 0 % E
% Phe: 0 7 7 0 0 0 0 7 0 0 0 7 0 0 0 % F
% Gly: 7 0 7 7 7 0 0 13 25 7 7 0 0 0 13 % G
% His: 0 19 0 7 7 0 0 7 0 50 0 0 0 7 0 % H
% Ile: 0 0 0 0 0 7 0 0 0 7 0 0 0 0 0 % I
% Lys: 7 7 7 0 7 0 0 0 0 0 44 0 0 0 0 % K
% Leu: 13 7 0 7 7 0 0 0 0 7 0 0 7 7 0 % L
% Met: 0 7 0 7 0 0 7 0 0 0 0 0 7 0 7 % M
% Asn: 0 0 32 0 0 13 0 0 13 7 0 0 0 0 0 % N
% Pro: 38 7 0 0 7 7 7 0 13 0 7 7 13 38 13 % P
% Gln: 0 38 13 0 0 0 7 0 7 7 7 50 0 7 7 % Q
% Arg: 0 0 0 0 7 7 7 0 0 0 7 0 0 7 0 % R
% Ser: 13 0 7 19 13 0 32 0 7 7 0 0 7 7 0 % S
% Thr: 0 0 7 7 25 0 0 7 7 0 0 7 0 0 0 % T
% Val: 0 0 0 0 7 7 0 0 13 0 7 0 0 7 7 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 7 44 0 0 7 13 44 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _