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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRC1 All Species: 5.45
Human Site: S532 Identified Species: 12
UniProt: O43663 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43663 NP_003972.1 620 71607 S532 P V A A S T C S G K K T P R T
Chimpanzee Pan troglodytes XP_510600 770 87232 L682 Y H S P V S R L P P S G S K P
Rhesus Macaque Macaca mulatta XP_001098763 640 74381 S532 P V A A S T C S G K K T P R T
Dog Lupus familis XP_849989 620 71878 L532 P I I T S T C L G K K T P Q A
Cat Felis silvestris
Mouse Mus musculus Q99K43 603 70244 L515 Y R S P M S R L P P S G S K S
Rat Rattus norvegicus NP_001100999 606 70580 L518 Y R S P M S R L P P S G S K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001073221 262 30135 S175 R R Q E E F V S I K R Q V I L
Frog Xenopus laevis NP_001080868 609 71186 C519 P V S R P P I C A G K P G L P
Zebra Danio Brachydanio rerio NP_956528 605 70353 P517 C H S P I S R P P I S A S K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572659 607 71048 A520 T N S P Q P A A A A K R N L I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785901 748 86941 L655 S V A A S P R L Y M S S A H S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.3 89.8 93 N.A. 81.2 81.2 N.A. N.A. 28.5 61.9 59 N.A. 22.2 N.A. N.A. 31.2
Protein Similarity: 100 78.4 92.5 95.8 N.A. 88.3 88.8 N.A. N.A. 35.6 76.2 73.3 N.A. 43.5 N.A. N.A. 48.1
P-Site Identity: 100 0 100 60 N.A. 0 0 N.A. N.A. 13.3 20 0 N.A. 6.6 N.A. N.A. 26.6
P-Site Similarity: 100 20 100 73.3 N.A. 26.6 26.6 N.A. N.A. 20 26.6 20 N.A. 20 N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 28 28 0 0 10 10 19 10 0 10 10 0 10 % A
% Cys: 10 0 0 0 0 0 28 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 28 10 0 28 10 0 10 % G
% His: 0 19 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 10 10 0 10 0 10 0 10 10 0 0 0 10 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 37 46 0 0 37 0 % K
% Leu: 0 0 0 0 0 0 0 46 0 0 0 0 0 19 10 % L
% Met: 0 0 0 0 19 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 37 0 0 46 10 28 0 10 37 28 0 10 28 0 19 % P
% Gln: 0 0 10 0 10 0 0 0 0 0 0 10 0 10 0 % Q
% Arg: 10 28 0 10 0 0 46 0 0 0 10 10 0 19 0 % R
% Ser: 10 0 55 0 37 37 0 28 0 0 46 10 37 0 28 % S
% Thr: 10 0 0 10 0 28 0 0 0 0 0 28 0 0 19 % T
% Val: 0 37 0 0 10 0 10 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 28 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _