Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRC1 All Species: 11.82
Human Site: S591 Identified Species: 26
UniProt: O43663 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43663 NP_003972.1 620 71607 S591 K D P S L S D S S T V G L Q R
Chimpanzee Pan troglodytes XP_510600 770 87232 S741 F S I N S V A S T Y S E F A R
Rhesus Macaque Macaca mulatta XP_001098763 640 74381 G591 S L S R R L L G E V E A D A D
Dog Lupus familis XP_849989 620 71878 S591 K D P S L S D S S T V G L Q R
Cat Felis silvestris
Mouse Mus musculus Q99K43 603 70244 S574 C S I K S V A S T Y S E F S R
Rat Rattus norvegicus NP_001100999 606 70580 S577 C S I K S V A S T Y S E F S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001073221 262 30135 M234 R R A L N E A M C A E L R S R
Frog Xenopus laevis NP_001080868 609 71186 S578 I S I N S V A S T Y S E F A R
Zebra Danio Brachydanio rerio NP_956528 605 70353 S576 F S I N S V A S T Y S E F Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572659 607 71048 K579 T G S R N P Q K I R P I P K I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785901 748 86941 S714 T G S S S A F S T S T V S G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.3 89.8 93 N.A. 81.2 81.2 N.A. N.A. 28.5 61.9 59 N.A. 22.2 N.A. N.A. 31.2
Protein Similarity: 100 78.4 92.5 95.8 N.A. 88.3 88.8 N.A. N.A. 35.6 76.2 73.3 N.A. 43.5 N.A. N.A. 48.1
P-Site Identity: 100 13.3 0 100 N.A. 13.3 13.3 N.A. N.A. 6.6 13.3 20 N.A. 0 N.A. N.A. 13.3
P-Site Similarity: 100 26.6 0 100 N.A. 20 20 N.A. N.A. 13.3 26.6 33.3 N.A. 6.6 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 10 55 0 0 10 0 10 0 28 0 % A
% Cys: 19 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 19 0 0 0 0 19 0 0 0 0 0 10 0 10 % D
% Glu: 0 0 0 0 0 10 0 0 10 0 19 46 0 0 0 % E
% Phe: 19 0 0 0 0 0 10 0 0 0 0 0 46 0 0 % F
% Gly: 0 19 0 0 0 0 0 10 0 0 0 19 0 10 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 46 0 0 0 0 0 10 0 0 10 0 0 10 % I
% Lys: 19 0 0 19 0 0 0 10 0 0 0 0 0 10 0 % K
% Leu: 0 10 0 10 19 10 10 0 0 0 0 10 19 0 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 28 19 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 19 0 0 10 0 0 0 0 10 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 28 0 % Q
% Arg: 10 10 0 19 10 0 0 0 0 10 0 0 10 0 73 % R
% Ser: 10 46 28 28 55 19 0 73 19 10 46 0 10 28 0 % S
% Thr: 19 0 0 0 0 0 0 0 55 19 10 0 0 0 0 % T
% Val: 0 0 0 0 0 46 0 0 0 10 19 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 46 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _