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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRC1
All Species:
8.79
Human Site:
T490
Identified Species:
19.33
UniProt:
O43663
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43663
NP_003972.1
620
71607
T490
G
K
A
R
K
L
N
T
T
T
M
S
N
A
T
Chimpanzee
Pan troglodytes
XP_510600
770
87232
G640
R
T
P
S
K
R
R
G
L
V
P
N
T
P
G
Rhesus Macaque
Macaca mulatta
XP_001098763
640
74381
T490
G
K
A
R
K
L
N
T
T
T
M
S
N
A
T
Dog
Lupus familis
XP_849989
620
71878
T490
G
K
V
R
K
L
N
T
T
T
M
S
N
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99K43
603
70244
K473
S
T
P
R
T
P
S
K
R
P
G
Q
T
P
K
Rat
Rattus norvegicus
NP_001100999
606
70580
G476
R
T
P
S
K
R
P
G
Q
T
P
N
K
C
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001073221
262
30135
I133
Q
D
K
N
L
C
D
I
L
C
V
S
N
F
S
Frog
Xenopus laevis
NP_001080868
609
71186
A477
P
N
K
R
R
M
I
A
P
S
T
P
S
K
C
Zebra Danio
Brachydanio rerio
NP_956528
605
70353
R475
I
R
T
P
T
K
R
R
F
L
G
S
T
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572659
607
71048
G478
K
S
N
R
G
I
H
G
S
T
S
S
L
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785901
748
86941
E613
N
A
R
K
R
I
T
E
E
E
M
L
H
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.3
89.8
93
N.A.
81.2
81.2
N.A.
N.A.
28.5
61.9
59
N.A.
22.2
N.A.
N.A.
31.2
Protein Similarity:
100
78.4
92.5
95.8
N.A.
88.3
88.8
N.A.
N.A.
35.6
76.2
73.3
N.A.
43.5
N.A.
N.A.
48.1
P-Site Identity:
100
6.6
100
93.3
N.A.
6.6
13.3
N.A.
N.A.
13.3
6.6
6.6
N.A.
20
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
100
93.3
N.A.
13.3
20
N.A.
N.A.
33.3
33.3
13.3
N.A.
40
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
19
0
0
0
0
10
0
0
0
0
0
28
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
10
0
0
0
10
10
% C
% Asp:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
10
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% F
% Gly:
28
0
0
0
10
0
0
28
0
0
19
0
0
10
19
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% H
% Ile:
10
0
0
0
0
19
10
10
0
0
0
0
0
0
0
% I
% Lys:
10
28
19
10
46
10
0
10
0
0
0
0
10
19
19
% K
% Leu:
0
0
0
0
10
28
0
0
19
10
0
10
10
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
37
0
0
0
0
% M
% Asn:
10
10
10
10
0
0
28
0
0
0
0
19
37
0
0
% N
% Pro:
10
0
28
10
0
10
10
0
10
10
19
10
0
19
10
% P
% Gln:
10
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% Q
% Arg:
19
10
10
55
19
19
19
10
10
0
0
0
0
0
0
% R
% Ser:
10
10
0
19
0
0
10
0
10
10
10
55
10
0
19
% S
% Thr:
0
28
10
0
19
0
10
28
28
46
10
0
28
10
28
% T
% Val:
0
0
10
0
0
0
0
0
0
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _